Corticosteroids Flashcards
1
Q
drugs included in this class
A
- Cortisone
- Prednisone
- Methylprednisolone
- Prednisolone
- Triamcinolone
- Betamethasone
2
Q
MOA
A
decrease inflammation and suppress immune system
3
Q
route
A
PO, IV, intraarticular, topical
4
Q
short term indications
A
disease flare, persistent disease activity despite treatment, when changing treatment (PO or intraarticular)
5
Q
long term indications
A
- may improve outcomes but but comes with risks
- these risks often outweigh the benefits !!!
6
Q
short term AEs
A
increase blood glucose, mood changes, fluid retention
7
Q
long term AEs
A
- osteoporosis
- increased fracture risk
- thin skin
- muscle wasting
- poor wound healing
- adrenal suppression
- Cushing’s disease
- increased risk of infection
8
Q
rehab concerns about corticosteroids
A
- osteoporosis
- adrenal suppression
