Alpha Adrenoceptor Blockers (-azosin)

Question 1

MOA

Answer 1

• reduce sympathetic tone of blood vessels
• vasodilation
• decreased peripheral vascular resistance

Question 2

these drugs are typically used as add-on drugs to reduce BP if…

Answer 2

one med isn’t enough

Question 3

AEs

hint: RONA

Answer 3

• reflex tachycardia
• OH
• nasal stuffiness
• arrhythmia

Question 4

therapeutic concerns

Answer 4

• first dose syncope –> fall precaution
• reflex tachy can cause angina in pt w poor cardiac perfusion
• increased incidence of CHF (look out for signs/symptoms)