Chlamydia

Question 1

Chlamydia - description

Answer 1

Family Chlamydiaceae - Obligate intracellular bacteria - Gram Negative - Elimentary vs. reticulate body

Question 2

Chlamydiaceae - Elimentary body

Answer 2

Infective

Question 3

Chlamydiaceae - Reticulate body

Answer 3

Metabolically active

Question 4

Chlamydiaceae - genuses

Answer 4

Chlamydia spp & Clamydophila spp.

Question 5

Chlamydiaceae - zoonotic species

Answer 5

Chlamydophila abortus, felis, pneumoniae

Question 6

C. abortus in Humans

Answer 6

Influenza-like illness - Abortion - Septicemia - Hepatitis - Kidney dysfuction - Pneumonia - DIC

Question 7

C. pneumoniae in humans

Answer 7

Zoonotic exposure not linked to any cases of human disease

Question 8

C. abortus in Sheep & Goats

Answer 8

Important cuase of enzootic late term abortion (may be carried asymptomatically)

Question 9

C felis in cats

Answer 9

Common cause of conjunctivitis - Blepharospasm, chemosis, congestion, ocular discharge - Mild to moderate rhinitis & pneumonitis

Question 10

Chlamydiaceae life cycle

Answer 10

Elimentary body (stable in env’t) taken up by host –> transforms into reticulate bodies (metabolically active) –> divide & differentiate into elementary body –> Released from cell

Question 11

Chlamydiaceae Transmission

Answer 11

Ingestion - Aerosol - Direct inoculation - Other abortion products - Venereal

Question 12

C. felis transmission

Answer 12

Shed in ocular & nasal secretions

Question 13

C. abortus lesion

Answer 13

Placentitis, relatively normal fetus, petechiae

Question 14

C. felis lesions

Answer 14

Conjunctivitis, rhinitis

Question 15

Chlamydiaceae treatments

Answer 15

Tetracycline, erythromycin, quinolones

Question 16

Chlamydiaceae prevention & warnings!

Answer 16

Pregnant women should avoid contact with pregnant or aborting ruminants! - Hygiene! - Use disease-free replacement stock