Chapter 5: Pharmacodynamics Flashcards
1
Q
pharmacodynamics
A
study of what drugs do to the body and how they do it
2
Q
Dose response relationships
A
- relationship between the size of an admonistered dose and the intensity of the response produced
3
Q
what 3 things does dose response relationship determine
A
- minimum amount of drug to be used
- maximum response a drug can elicit
- how much to increase the dosage to produce the desired increase in response
4
Q
as dose increases, response becomes
A
larger
5
Q
how is dose response relationship used for treatment
A
- increased or decreasing the dosage until the desired intensity is achieved
*some drugs increasing dosage does not increase therapeutic effect, the response is more adverse side effects
6
Q
maximal efficacy
A
- largest effect that a drug can produce (height of the curve)
7
Q
relative potency
A
- the amount of drug that must be given to elicit an effect
- refers to dosage needed to produce effects
8
Q
two characteristic properties of drugs revealed in dose-response corves
A
- maximal efficacy
- relative potency
9
Q
drugs
A
chemical that produce effects by interacting with other chemical
10
Q
receptors
A
- special chemical in the body that most drugs interact with to produce effects
11
Q
receptor activity is regulated by
A
endogenous compounds
12
Q
the more selective a drug is
A
the fewer side effects it will produce
13
Q
receptors operate ina _______ mechanism
A
lock and key
14
Q
what does the body have recpetors for
A
- neurotransmitters
- hormones
- all other molecules in the body used to regulate physiologic processes
15
Q
affinity
A
drugs attraction to a receptor
