Chapter 1: Orientation to Pharmacology Flashcards
Pharmacology is a science that draws on information from multiple disciplines, including: (5)
- anatomy
- physiology
- psychology
- chemistry
- microbiology
drug definition
- any chemical that can affect living processes
pharmacology definition
study of drugs and their interactions with living systems
Clinical Pharmacology defintion
- study of drugs in humans
therapeutics is also known as
pharmacotherapeutics
Therapeutics defintion
- the use of drugs to diagnose, prevent, or treat disease
- the medical use of drugs
what are the three most important properties of an ideal drug
- effectiveness
- saftey
- selectivity
what is the most important property a drug can have
effectiveness
selectivity
- drug elicits only the response for which it is given
is there such thing as a fully selective drug
no
what is the therapeutic objective
provide maximum benefit with minimal harm
what are the additional properties of an ideal drug
- reversible action
- predictability
- ease of administration
- freedom from drug interactions
- low cost
- chemical stability
- simple generic name
what are the 4 factors that determine the intensity of drug responses
- administration
- pharmacokinetics
- pharmacodynamics
- sources of individual variation
administration (definition and examples)
important determinants of drug responses
EXAMPLES: dosage amount, routes and timing, patient adherence
pharmacokinetics (definition and examples)
determining how much of the administered dose gets to its sites of actions
EXAMPLES: absorption, distribution, metabolism and excretion
