Chapter 49: Vasodilators Flashcards

1
Q

hat are the therapeutic uses of vasodilators

A
  • essential hypertension
  • hypertensive crisis
  • angina pectoris
  • heart failure
  • myocardial infraction
  • pheochromocytoma
  • peripheral vascular disease
  • pulmonary arterial hypertension
  • production of controlled hypotension during surgery
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2
Q

adverse affects of vasodilators

A
  • postural hypotension
  • reflex tachycardia
  • expansion of blood volume
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3
Q

patients taking vasodilators are at increased risk of

A

FALLS

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4
Q

Hydralazine [apresoline] therapeutic uses

A
  • essential hypertension
  • hypertensive crisis
  • heart failure
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5
Q

Hydralazine [Apresoline] effects

A
  • reflex tachycardia
  • increased blood volume
  • systemic lupus erythematosus-like syndrome
  • headache, dizziness, weakness, and fatigue
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6
Q

hydralazine [Apresoline] MOA

A
  • selective dialation of arterioles; little or no effect on veins
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7
Q

Minoxidil MOA

A

selective dilation of arterioles
- more intense than hydralazine; but more adverse reactions

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8
Q

Minoxidil is used for

A

severe hypertension that is unresponsive to safer drugs

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9
Q

Minoxidil adverse effects

A
  • reflex tachycardia
  • sodium and water retention
  • hypertrichosis
  • pericardial effusion
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10
Q

Sodium Nitroprusside [Nitropress] MOA

A
  • fast acting antihypertensive agent
  • causes venous and arteriolar dilation
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11
Q

Sodium Nitroprusside [Nitropress] onset

A

immediate (BP returns to pretreatment level in minutes when stopped)

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12
Q

Sodium Nitroprusside [Nitropress] is used for

A

hypertensive emergencies

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13
Q

Sodium Nitroprusside [Nitropress] adverse effects

A
  • excessive hypotension
  • thiocyanate toxicity
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