Chapter 20: Adrenergic Agonists Flashcards
Adrenergic Agonists are also called
sympathomimetic
adrenergic agonists have applications in
- congestive heart failure
- asthma
- preterm labor
epinephrine receptor specificity
- alpha1 and alpha2
- beta1 and beta2
Adrenergic receptor activation effect on Atrioventricular (AV) heart block
- enhance impulse conduction through AV node
- can help overcome AV block
- drugs= temporary form of treatment
long term management of AV heart block
pacemaker
cardiac arrest treatment
Epinephrine
- IV/direct injection into the heart
anaphylactic
- severe allergic response
- hypotension, bronchoconstriction, edema of the glottis
treatment of anaphylaxis
epinephrine
therapeutic uses of epinephrine
- delays absorption of local anesthetic
- controls superficial bleeding
- elevates blood pressure
- overcomes AV block
- restores cardiac functioning during arrest
- causes bronchial dilation in patients with asthma
- treatment of choice for anaphylactic shock
epinephrine absorption
- intramuscular (IM), subcutaneous (SQ), and intravenous (IV)
epinephrine half life
short
adverse effects of epinephrine
- hypertensive crisis
- dysrhythmias
- Angina pectoris
- necrosis after extravasation
- hyperglycemia
what patients are at high risk for dysrhythmias
patients with hyperthyroidism
patients at risk for angina pectoris are patients with
coronary atherosclerosis
norepinephrine recept specificity
- alpha1
- alpha2
- beta1
chemical classification of norepinephrine
catecholamine
therapeutic uses of norepinephrine
- hypotensive states
- cardiac arrest
how does norepinephrine differ from epinephrine
does not activate beta2 receptors (does not promote hyperglycemia)
norepinephrine cannot be given
orally
isoproterenol receptor specificity
beta1 and beta2
isoproterenol chemical classification
catecholamine
isoproterenol therapeutic uses
Cardiovascular
- AV heart block
- cardiac arrest
- increase cardiac output during shock
isoproterenol adverse effects
- tachydysrhythmias and angina pectoris
- hyperglycemia in patients with diabetes
administration of isoproterenol
- IV, IM, and intracardiac injections
