Chapter 32 Flashcards
The kidneys receive about what percent of cardiac output?
20%
the kidneys require large _____ _____
blood flow
functional unit of kidney
nephron
each kidneys contains about how many nephrons?
1.2 million
what does the juxtaglomerular appartus/cell do?
controls blood flow, glomerular filtration, renin secretion, urine flow and composition
what is the function of the nephron?
glomerular filtration, reabsorb water, electrolytes and other sub needed to maintain the constancy of the internal environment into the blood stream
components of nephron:
glomerulus, bowmans capsule, proximal and distal tubule, loop of henle, collecting tubule.
contains the glomerulus. acts as a reservior for glomerular filtrate
bowman’s capsule
network of capillaries/blood vessels actively involved in the filtration of the blood to form urine. blood flow. deposits ultrafiltrate.
glomerulus
function of the tubules
controls what is held on to and what is released
vital functions of the kidney
- detoxification of the blood and eliminating waste
- regulation of blood pressure
- maintaining fluid and acid-base balance
- regulation of electrolytes
- help maintain RBC levels
- regulating vitmain D and calicum formation
urea: by product of
ammonia from liver
creatinine: by product of
skeletal muscle
uric acid: small amounts excreted in
urine
what system helps regulate BP?
RAAS system
helps maintain RBC
erythropoietin
regulating vitamin D and calicum formation: through _________ to _______ form
through conversion to active form
urinalysis
- color
- apperance
- specific gravity: 1.005-1.025
- pH: 4.5-8
- glucose : negative
- ketones: negative
- proteins: negative
- RBCs: rare or none
- nitrate: negative
glomerular filtration rate:
filtration of plasma into the bowman space. all kidney functions, including endocrine, are related to GFR.
normal GFR:
115-125 ml/min
the complete removal of substance from the blood in 1 minute
renal clearance
the volume of blood that can be cleared of creatinine in 1 minute
creatinine clearance
what is the most accurate measurement of glomerular filtration
creatinine clearance (24 hour urine)
if GFR increase,
urine output will increase
serum creatinine =
.5-1.5 mg/dL
blood urea nitrogen:
5-25 mg/dL