Chapter 18 Part 3 Endocrine Glands Flashcards

1
Q

What are also known as surparenal glands

A

adrenal glands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are located superior to the kidney, in the retroperitoneal area, are surrounded by adipose tissue

A

adrenal glands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The adrenal glands are very _____ organs

A

vascular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

There is a central vein in each adrenal glands

The right drains into ____

the left drains into ______

A

IVC

Left Renal vein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the 3 parts of the adrenal cortex?

A

zona glomerulosa
zona fasciculata
zona reticularis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what part of the adrenal cortex is small cell clusters

A

zona glomerulosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Mineralcorticoids =

A

aldosterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What part of the adrenal cortex is the thickest layer, with long columns

A

Zone fasciculata

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

glucocorticoids =

A

cortisol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What part of the adrenal cortex is thin, irregular cords and cells

A

zone reticularis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

gonadocorticoids

A

angrogens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What part of the adrenal gland is made of nervous tissue

A

adrenal medualla

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

The adrenal medulla produced catecholamines in what percentage

A

Epi - 80%

Norepi - 20%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

The adrenal cortex secretes

A

Corticosteroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What have a long hald life, lipid soluble, and are slow acting

A

corticosteroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What have short half life and are fast acting with neural control

A

catecholamines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the primary mineralocorticoid and is regulated by renin-angiotensin

A

aldosterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what is the target of aldosterone

A

kidney

(reabsorbs salt and H20)

19
Q

What role of aldosterone is to …

A

regualte ion blance in the blood of Na and K

20
Q

If there is excess aldosterone there is

A

low blood K+ and alkalosis

21
Q

What is regulated by - feedback circadian ACTH release as a stress repsonse

22
Q

What is the role of cortisol?

A

decreases inflammatory and immune response

23
Q

When does cortisol blood levels peak?

A

shortly before rise

24
Q

When is cortisol the lowest?

25
What are stressors that cause the release of cortisol
hemorrhage, infection, and trauma
26
What is the stress hormone
cortisol
27
If cortisol is elevated what in the body can be adversely affected?
metabolic immune connective tissue bone calcium levels cardiovascular CNS gastrointestinal
28
What are the most common adrenal sex hormones
weak androgens (DHEA
29
What is converted to more potent testosterone and estrogen in cells
adrenal sex hormones
30
What is the role of adrenal sex hormones
to develop secondary male sex characteristics or stimulate female puberty and sex drive
31
What disorder involves hyposecretion of mineralocorticoids and glucocorticoids
addisons disease
32
with adrenocorticoid deficiency you need to add
steroids
33
What is the cause addisons disease
autoimmune destruction of adrenal cortex
34
ACTH levels are high in Addison's disease due to
- feedback of low cortisol
35
symptoms of addisons
bronzing disease lose weight weakness GI issues Muscle cramping dehydration low BP
36
excess stress with addisons can cause
adrenal crisis
37
What is the treatment of addisons
steroid hormone replacement hydrocortisone to mimic circadian cycle
38
what is the acute complication of adrenal insufficiency due to physiological stress or illness
adrenal crisis
39
How do you treat adrenal crisis
treat emergently with corticosteroid injections
40
Adrenal crisis Sx
joint pain hypotension hypoglycemia vomiting loss of consciousness fever fatigue confused back pain hair loss
41
What disease is a hypersecretion of glucocorticoids (too much cortisol)
cushings
42
what causes cushings
ACTH tumors cortisol drugs
43
What are symptoms of cushings
cushingoid = moon face, buffalo hump, easy briuse, poor wound healing, elevated BS, muscle bone protein loss, water/salt retention, hypertension edema
44
What is the treatment of cushings
remove tumor cause and stop meds