Cardiac DZ Flashcards
S3 murmur suggests? normal in what pts?
Mitral Regurg
children and pregnant women
S4 suggests?
LV hypertrophy
Pt with sycope, angina and dyspena. Heart murmur?
AS
Pt with head bobbing - murmur?
AR
Pt with tosades de pointes - Tx?
Mg sulfate
Pt with defects in cardiac Na/K pumps and congenital sensorineural deafness?
Congenital long QT syndrome.
Jervell and Lange-Nielsen syndrome
saw-tooth ECG with random QRS complexes. Tx?
A-FLUTTER. B-blocker or Ca-channel inhibitor
Pt with abnormal ECG has stroke. ECG would likely show?
A-fib. Can lead to cardiac stasis
Pt with hypertension, bradycardia and repiratory depression. Mech?
increased ICP cuases arteriolar constriction - results in cerebral ischemia
Ischemia causes increase in BP -
Stretching of baroreceptors causes a decrease in HR
Pt with cyanosis, polycythemia and clubbing. ECHO shows RV hypertrophy. Cause?
Uncorrected congential R-to-L defect that switched (eisenmenger’s syndrome).
VSD, ASD, PDA
Pt with notching of ribs and weak pedal pulses. Also may have?
Adult-type coarctation. Bicuspid aortic valvue
New born with machine murmur of heart. Tx?
PDA. Given endomethacin
Pt with 22q11 - Heart defect?
Truncus arteriosus and tetralogy of Fallot
Pt with Down syndrome - Heart defect?
endocardial cushion defects: ASD, VSD, AV septal defect
pt with congential rubella - Heart defect?
septal defects, PDA, pul artery stenosis
Mother with diabeties - Heart defect of child?
transposition of great vessels
Freiderich’s ataxia - death from?
Hypertrophic cardiomyopathy
Pt with Left flank pain, pulsitile ab mass. Will see what on imaging?
Ruptured Ab aortic aneurysm
Pt with with chest pain has CXR. Mediastinal widening?
Aortic dissection
Pt with Marfan’s suddenly dies. Cause?
MVP (Aortic dissection can’t cause sudden death)
Pt with ST-elevated MI. Which artery most likely?
LAD>R coronary>LCA
Pt who dies from sudden cardiac death post MI. Cause?
V-Fib
Pt with S4, apical impulses and systolic murmur. Tx?
HCM. S4 - difficultly filling LV. B-blocker or non-dhydropyridine ca-channel blocker
Pt with S3, balloon appearance on CXR. Tx?
Dilated cardiomyopathy. Restrict Na, ACE inhibitors, digoxin.
Pt with endomyocardial fibrosis and eosinophils?
Lofflers. Restrictive CM
Improves symptoms and mortality in CHF patients?
B-blockers, hydralazine, nitrate therapy
Pt with white spots on retina, painful raised lesions on pads of fingers and flat red lesions on plams?
Bacterial Endocarditis. Roth’s spots, oslers nodes and janeway lesions.
Pt with tricuspid endocarditis. IV drug user. Organisms?
S aureus, pseudomonas, Candida
Most common cause of bacterial endocarditis?
Viridans
Pt comes in with head bobbing, and horseness. Postive VDRL. Mech?
Syphilis. AR from vasa vasorum infiltration and horseness from dilation impinging on recurrent laryngeal
Pt with ball shaped obstruction in LA?
Myxoma.
Pt dies of heart failure. Biopsy shows lymphocytes in myocardium.
Coxsackie
Pt comes in with joint pain, a unilateral headache and a high ESR. Says it hurts to chew. Biopsy would show?
Temporal arteritis. Granulomas
Young woman comes in with weak upper extremitiy pulses, arthritis and vision distrubances. Increased ESR. Where specifically is affected?
Takayasu’s. Aortic Arch
Pt with abdominal pain, melena, fever, weight loss, skin lesions of different ages. Vessels most likely to be affected?
PAN. Renal and visceral vessels.
Pt with Hep B gets renal damage and skin eruptions. Biopsy would show?
PAN. Transmural inflammation of arterial wall
Child with high fever, conjunctivitis and swelling of hand/foot. Complication?
Kawasakis. MI
Child with fever, red tongue, and desquamating rash. Negative for strep. Tx?
Kawasakis. Aspirin
Pt comes in with gangrene and autoamputation of fingers. Tx?
Buerger’s. stop smoking
Pt with perforation of nasal septum, chronic sinusitis and otitis media. ALso has hematuria.
Wegners
Pt with asthma gets wrist drop and palpable purpura? Biopsy shows?
Churg straus. Necrotizing vasculitis with eosinophilia.
Pt with palpable purapura on buttocks, joint pain and melena?
Henoch-Schonlein purpura
Pt comes in with spider angioma. Cause?
Estrogen
Infant comes in (few weeks post birth) with red growth on skin. Tx? Over time, development of lesion?
Strawberry hemangioma. None. Initally increases in size with growth of child but will regress by 5-8 years
Vessel growth seen in pregnancy? Complication?
Pyogenic granuloma? Hemangioma that can ulcerate and bleed
Pt with red-blue mass under nail? Composed of?
glomus tumor from SMCs
Pt recieving radiation treatment for breast cancer comes in with a red growth on arm.
Angiosarcoma
Pt post-radical masectomy. Growth in axilia.
Lymphoangiosarcoma
Pt with large mark on face, and seizures. Mech? Complication?
Struge-Weber disease. Affects capillary sized bloody vessels. Complication are leptomeningeal angiomatosis, intracerebral AVM on same side as face lesion
Pathogenesis of a atheroclerotic plaque
1) EC dysfuntion
2) Macrophage and lipid accumulation
3) Platelets release PDGF and TGF-B to promote SMC migration
4) SMCs make ECM
Pt with transmural inflammation with fibrinoid necrosis of blood vessels?
PAN
Pt has dilated and tortuous superficial veins on lower legs. Complication?
Varicose veins. Skin ulceration
Smoker with exertional calf pain and painful foot ulcers. Cause? Mech of nerve pain?
Buergers. Vasculitis extends to nerves.
Pt with bright red central papule surrounded by outwardly radiating vessels. Lesion dependent on?
Spider angiomas. Estrogen
Pt with myxomatous degeneration of vessels. Likely will result in? (if myxomatous degeneration in heart?)
Aneurysm. Mitral valve destruction. (Myxomatous suggests degeneration of connective tissue)
Pt exposed to arsenic and polyvinyl chloride. Develops what tumor? Marker?
Liver angiosarcoma. CD31
Pt with edema in veins with varicose veins. Defect in?
Venus valves
Pt with huge edema. Cause?
obstruction of lymph nodes. results in elephantitis
Pt with vague abdominal discomfort. Centrally located, pulsatile mass. Initial injury?
Ab Aortic Aneurysm. Causes primary by athlerosclerosis. (Medial degeneration is distant second)
Pt with palpable purpura, and transmural necrotizing inflammation of vessels. Will not affect which vessels?
PAN. Pulmonary
Pt with low lipoprotein lipase activity. How will pt present to hospital?
Familal hyperchylomicronemia. Increased risk for pancreatitis.
Pt with aortic dissection. Most likely cause?
HTN
Pt with homogenously thickened arteriolar vessel walls? Causes?
Hyaline arteroloscelorsis. DM and HTN
Elderly pt with HTN. Normal age related change why?
Stiffening of aorta with Age
Pt with tetralogy of fallot squats when cyanotic. Why?
Increases preload and increases systemic vascular resistance. Increased TPR forces more blood into the lungs.