breast - recap Flashcards
fibroadenoma
- symptoms
- Mx
25-35years
lump - mobile, regular
painless
fibrocystic/ fibroadenosis
- symptoms
- Mx
green nipple discharge rope-like- palptation mastalgia tenderness cyclical Mx - reassure, supportive bra, avoid caffeine, apply heat, antiinflam, eve topical primrose oil, COCP
breast cyst
- symptoms
- Mx
30-50yrs, perimeno
fluid-filled lump, fluctuant, mobile, well-circumscribed
uss drainage
biological therapy
- what
- why
HER2 +ve
herceptin - affects heart so close monitoring
perjeta - combo with herceptin
neratinib - tyrosine kinase inhibtor, DE growth
biological therapy
- what
- why
HER2 +ve
herceptin (trastuzumab; HER-2 MCA) - affects heart so close monitoring
perjeta (HER-2 MCA) - combo with herceptin
neratinib - tyrosine kinase inhibtor, DE growth
insitu ductal carcinoma
- %
- what
- mx
5%
pre cancerous, found on mammogram as microcalfications
30% become invasive
invasive ductal carcinoma
- %
- what
- mx
90% of invasive
cancerous
mx - as per management of bc
insitu lobular carcinoma
- %
- what
- mx
5%
precancerous and premeno
6 monthly exam and mammo
invasive lobular carcinoma
- %
- what
- mx
10% of invasive
manage as breast cancer
inflammatory breast cancer
erythema, oedema, warm, painful
poor prognosis
cancerous
phylloides tumour
stromal tumour of breast
anastrozole - SE
osteoporosis
hot flushes
arthralgia, myalgia
insomnia
tamoxifen (SERM) - SE
endometrial cancer
hot flushes
VTE
menstrual - vag bleed, amenorrhoea
imaging - breast
<35yrs - USS
>35yrs or asymptomatic - mammogram
wide local excision combined with
adjuvant radiotherapay
