Blood Vessels and Circulation Flashcards
Blood vessels classified by histological organization
largest vessels attached to the heart
-aorta - carries blood from left ventricle to to systemic circulation
-pulmonary trunk - carries blood from right ventricle to to pulmonary circulation
arteries, arterioles and capillaries
-arteries - carries blood away from the heart
-arterioles - smallest branches of arteries that lead to capillary beds
-capillaries - smallest blood vessels with thin walls, location of ezchange between blood and interstitial fluid
venules
-smallest branches of veins that collect blood from capillaries
veins
-return blood to heart
vessel walls
-tunica intima
-tunica media
-tunica externa
tunica intima
-inner layer
-endothelial lining
-connective tissue layer
-intenral elastic membrane (elastic fibers in outer margin)
tunica media
-concentric sheets of smooth muscle in loose connective tissue
-encircles the endothelium that lines the lumen of the blood vessels
-binds to inner and outer layers
-external elastic membrane
tunica externa
-anchors vessel to adjacent tissue
-collagen fibres, elastic fibers and smooth muscles (only in veins)
-vasa vasorum
vasa vasorum
-small arteries and veins in walls of large arteries and veins
-serve cells of tunica media and tunica externa
differences between artery and vein
artery
-round with thick wall
tunica intima
-usually rippled due to vessel constriction
-internal elastic membrane
tunica media
-thick, dominated by smooth muscle cells and elastic fibers
-external elastic membrane present
tunica externa
-collagen and elastic fibers
Vein
-uaully flattened or collapsed with relatively thin wall
-tunica intima
-often smooth
-internal elastic membrane is not present
tunica media
-thin dominated by smooth muscle cells and collagen fibers
-ecternal elatic membrane is absent
tunica externa
-collagen and elastic fibers and smooth muscle cells
differences between arteries and veins part 2
-arteries have thicker walls and higher blood pressure than veins
-a constricted artery has small round lumen
-a vein has a large irregular lumen
-the endothelium of a constricted artery is folded
-arteis are more elastic than veins
-veins have valve
arteries contractility and elasticity
-elasticity allows arteries to absorb pressure waves that come with each heartbeat
-contractility
arterties chamge diameter
controlled by sympathetic division of ANS
vasoconstriction/vasodilation
-contraction or relaxation of smooth muscle
vasodilation and vasoconstriction affect
-afterload on heart
-peropheral blood pressire
-capillary blood flowf
from heart to capillaries arteries change from
-from elastic arteries
-to muscular arteries
-to arterioles
elastic arteries
-large vessels
-tunica media has many elastic fiberes and few muscle cells
-elasticity evens out pulse force
muscular arteries
-most arteries are medium sized muscular arteries
-tunica media has many muscle cells
arterioles
-small vessels
-have little or no tunica externa
-have thin or incomplete tunica media
aneurysm
-a bulge in an arterial wall
-caused by weak spot in elastic fibers
-pressure may rupture vessel
arteries vs beins histological
capillaries
-smallest vessels with thin walls
-microscopic capillary networks permeate all active tissues
-location of all exchange functions of cardiovascular system
-materials diffuse between blood and interstitial fluid
capillary structure
-endothelial tube, indise basement membrane
-no tunica media
-no tunica externa
-diameter is similar to that of RBCc
continous capillaries
-found in all tissue except epithelia and cartilage
-have complete endothelial lining
-permit diffusion of water small solutes and lipid soluble material
-block blood cells and plasma proteins
-specialized continuous capillaries in CNS and thymus have very restricted permability (restricted, BBB)
fenestrated capillaries
-have pores in endothelial lining
-permit rapid exchange of water and larger solutes
-found in: choroid plexus, endocrine organs, kidneys, intestinal tract
sinusoids/sinusoidal capillaries
-have gaps between adjacent endothelial cells
-permit free exchange of water and large plasma proteins
-found in: liver, spleen, bone marrow, endocrine organs
-phagocytotic cells monitor blood at sinusoids
photo of capillaries
capillary beds
-connect one arteriole and one venule
precapillary sphincter
-guards entrance to each capillary
-opens and closes causing capillary blood to flow in pulses
thoroghfare channels
-direct capillary connections between arterioles and venules
collaterals
-multiple arteries that contribute to one capillary bed
-allow circulation if one artery is blocked
arterial anastomosis
-fusion of two collateral arteries
arteriovenous anastomoses
-direct connections between arterioles and venules
-bypass the capillary bed
angiogenesis
-formulation of new blood vessels
-stimulated by vascular endothelial growth factor
-occurs in the embryo as organs develop
-occurs in response to factors released that are hypoxic or oxygen starved
-most important in cardiac muscle inr esponse to a chronically constricted or occluded blood vessle
compared to arteries veins have
-larger diameters
-thinner walls
-lower blood pressure
venules
-very small veins
-collect blood from capillaries
medium sized veins
-thin tunica media and few smooth muscle cells
-tunica externa contains longitudinal bundles of elastic fibers
large veins
-have all three tunica layer
-thick tunica externa
-thin tunica media