Blood Flashcards

1
Q

blood overview

A
  • type of connective tissue

- two main portions: liquid + cells

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2
Q

liquid of blood

A

plasma

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3
Q

formed elements

A

the cells found in blood: red blood cells, white blood cells, and platelets

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4
Q

serum

A
  • plasma with the clotting factors removed

- commonly used for lab tests

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5
Q

functions of plasma (4)

A
  • helps buffer pH of blood
  • aids in coagulation (blood clotting)
  • assists in transporting large organic molecules in blood
  • contains proteins that maintain blood’s osmotic pressure
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6
Q

pH of blood

A

~ 7.4

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7
Q

osmotic pressure

A
  • net pressure in blood that moves fluid from tissues into the circulatory system
  • maintained by proteins in plasma - naturally attract water from tissues into the capillaries
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8
Q

hydrostatic pressure

A

pressure of blood pumping from heart that pushes fluid into tissues

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9
Q

osmotic vs. hydrostatic pressure

A
  • oppose each other

- balance of this opposition is important for homeostasis

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10
Q

hemoglobin

A
  • helps red blood cells carry oxygen
  • ~250 million hemoglobin molecules per red blood cell
  • when old blood cell destroyed, hemoglobin released so iron can be recycled and reused by the red bone marrow
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11
Q

amt red blood cells in blood

A

4 - 6 million per 1mm3 whole blood

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12
Q

red blood cells overview

A
  • small biconcave disks
  • most abundant cell in blood
  • anucleate (lose nucleus + synthesize hemoglobin in order to enter blood stream)
  • function = carry oxygen
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13
Q

red bone marrow

A
  • found in skull, ribs, vert, ends of long bones

- continuously manufactures red blood cells

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14
Q

life span of red blood cells

A
  • live ~ 120 days
  • destroyed by liver and spleen
  • hemoglobin is recycled but heme is degraded and excreted by liver as bile pigment
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15
Q

white blood cells overview

A
  • aka leukocytes
  • larger than red blood cells
  • large nucleus
  • no hemoglobin
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16
Q

white blood cells function

A

inflammatory response to microorganism entering body through injury to blood vessel
how it works:
- blood flow to site of injury increases to bring white blood cells (that’s what causes redness and swelling)
- white blood cells squeeze through capillaries and enter tissue fluid, where destroy any foreign materials

17
Q

pus

A

thick yellowish fluid that contains lots of dead white blood cells

18
Q

3 groups of white blood cells

A
  1. granulocytes (contain granules in cytoplasm)
  2. agranulocytes (no granules in cytoplasm)
  3. lymphocytes
19
Q

types of granulocytes (3)

A

neutrophils
eosinophils
basophils

20
Q

types of lymphocytes (2)

A

T-Cells

B-Cells

21
Q

blood platelets

A
  • aka thrombocytes
  • fragments of megakaryocytes (large bone marrow predecessor)
  • involved in coagulation – stick to edge of wound + clot the opening, release chemicals to signal coagulation cascade
22
Q

coagulation cascade

A

series of events to start blood clotting mechanism

23
Q

prothombrin activator

A
  • clotting factor
  • released by platelets and injured tissue (start of coagulation cascade)
  • converts prothombrin to thombrin
24
Q

thombrin

A

converts fibrinogen to fibrin

25
Q

fibrinogen

A

substance from the liver floating in blood

26
Q

fibrin

A
  • threads that wind around platelet plug (damaged area) to form framework for clot
  • red blood cells get trapped in thread to form red looking clot
27
Q

plasmin

A

enzyme that destroys fibrin clot once blood vessel repair begins