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Advanced Pharm > Behavioral Med Drugs I > Flashcards

Behavioral Med Drugs I Flashcards

1
Q

This class of drugs reduces sleep latency time

A

hypnosis

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2
Q

What are some other effects of sedatives

A

prevent seizures, muscle relaxant

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3
Q

Most intentional and accidental overdoses involve ____

A

polypharmacy

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4
Q

This is an ultra-short action of induction of anesthesia with onset <1 minute, duration of 20 minutes

A

thiopental

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5
Q

This is a short acting hypnotic lasting 3-8 hrs

A

Pentobarbital, amo/seco barbital

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6
Q

This is a long acing barbituate lasting 1-2 days, was used in kids

A

phenobarbital

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7
Q

What is one of the main reasons why there is a decline in the barbiturate utilization

A

high overdose potential

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8
Q

What receptor type does GABA work on ?

A

GABA-A

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9
Q

This is the main CNS inhibitory neurotransmitter

A

GABA

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10
Q

GABA A-1 mediates this:

A

anesthesia and sedation

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11
Q

GABA A-2 mediates this

A

anticonvulsants, anxiolytic actions

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12
Q

These benzos have utility in sedation

A

alprazolam, and lorazepam

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13
Q

This is a benzo antagonist that is used parentally needs to be available for outpatient procedures with conscious sedation and it used to reverse it.

A

flumazenil

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14
Q

The first generation of antihistamines included what side effects?

A

drowsiness/sedation

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15
Q

This is an H1 receptor antagonist that has strong sedation effects

A

Hydroxyzine

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16
Q

This sedative has an anxiolytic effect with less cognitive dysfunction, decreased abuse potential, and less effective in panic disorders

A

Buspirone

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17
Q

How long do you use hypnotic therapy

A

2 wks or less

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18
Q

What non-benzo hypnotic has an increase in the incidence of depression

A

eszopiclone

19
Q

This type of depression is considered a normal reaction to tragedy

A

reactive

20
Q

This type of depression is hypothesized to be a neurotransmitter imbalance

A

endogenous

21
Q

This type of depression is alternating periods of mania and depression

A

bipolar affective disorder

22
Q

What is the main stay of bipolar tx and examples

A

mood stabilizers: lithium, anticonvulsants

23
Q

How do you tx the manic phase of bipolar disorder

A

antipsychotic drugs

24
Q

What are some cautions of lithium carbonate?

A

narrow therapeutic index, multiple drug interactions

25
Q

What are the 4 General Rules about Antidepressants?

A
  1. effectiveness of each group is equal
  2. none work quickly
  3. side effect profiles differ significantly
  4. safety issues also differ
26
Q

What adverse effect of MAOIs is similar to a thyroid storm?

A

tyramine crisis

27
Q

T/F, tyramine is in foods

A

True

28
Q

What are other indications of MAOIs?

A

neurotic disorders, PTSD, OCD, Parkinson

29
Q

What is a serious adverse effect of MAOIs?

A

overdose potential

30
Q

TCA are effective but what is a significant issue?

A

safety

31
Q

What are TCA side effects?

A

anticholinergic, orthostatic hypotension, reflex tachy

32
Q

What is the main indication of TAC?

A

chronic depression

33
Q

Name two 1st generation TCAs

A

Imipramine, amitriptyline

34
Q

What are other uses of SSRIs?

A

eating disorders, OCD, panic attacks, PMS, postmenopausal vasomotor flushes

35
Q

What are popular choices of SSRIs?

A

fluoxitine, paroxetine, sertaline, escitalopram, citalopram

36
Q

What are the SSRI side effects?

A

sleep disturbances, sexual dysfunction, almost zero risk of fatal overdose

37
Q

This antidepressant is most effective against neuropathic pain

A

SNRIs

38
Q

Examples of SNRIs

A

Venlafaxine, Duloxetine

39
Q

What are two examples of atypical antidepressants?

A

buproprion, trazadone

40
Q

This drug has potent antidepressant effects with a very rapid onset of action

A

Ketamine

41
Q

What are some other uses for antidepressants?

A

chronic pain/fibromyalgia, enuresis, smoking cessation, migraine headaches, postmenopause

42
Q

What are some suicide warnings for antidepressants?

A

highest risk in the first few months, special caution in teens/young adults

43
Q

T/F psychotropic drugs are approved for use in pregnancy

A

False

44
Q

This is seen in pt stopping or reducing the dose of antidepressants

A

discontinuation syndrome

Advanced Pharm (23 decks)

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