Autonomic II Flashcards
Exam I
sympathetic ocular response
mydriasis (big)
sympathetic pulmonary response
dilate
adrenergic receptors alpha-1
vascular, pupil, piloerection
adrenergic receptors beta-1
heart
adrenergic receptor beta 2
smooth muscle (bronchioles, uterus, vascular)
aphla-1 adrenergic receptors causes
vasconstriction, increased sphintcher tone
beta-1 adrenergic receptor causes
increased heart rate
beta-2 adrenergic receptor causes
bronchiole dilation, uterine
3rd not so well know adrenergic agonist, not used
isoproterenol
dopamine’s major importances
CNS, renal and splanchnic vasculature
epinephrine has the same effects on both alpha and beta receptors T/F
TRUE
norepi has the same receptor effects in alpha receptors T/F
TRUE
Norepi has a greater effect on which beta receptor
B1
indications for epi
anaphylactic shock, acute asthma
Drugs drip and infusion for shock tx
norepi and dopamine
Alpha agonist indications
topical for nasal congestion and HTN tx
prolonged vasoconstriction leads to hypoxia which causes vasodilation and ultimately ___.
reactive hyperemia
indications for beta agonists
severe CHF, cardiac shock, asthma, premature labor
alpha blocker indications
HTN, BPH
beta blocker indications
HTN, hyperthyroid, benign tremors, afib
do not use beta blockers in these 4 cases
- asthma, 2. avoid sudden withdrawl in arrhythmias, 3. uncompensated CHF, 4. bradycardia
Receptors are blocked, the target cells in myocardium tend to produce more receptors d/t them not getting enough of the drug they need
Why is there an increased risk of cardiac arhythmias with abrupt beta blocker withdrawl?
