August 27, 2015 - Pancreas and Bile Duct Cancer Flashcards

1
Q

5-Year Relative Survival of Pancreatic Cancer

A

Extremely poor. Between 5-7%. This is one of the worst cancers you can get.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Risk Factors for Pancreatic Cancer

A

Obesity

Diabetes

Cigarette smoking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Cholangiocarcinoma Location

A

May be intrahepatic, perihilar (most often), or distal.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Intrahepatic CCA Presentation

A

Usually asymptomatic.

Usually not jaundiced.

Usually just with constitutional symptoms such as fatigue, malaise, anorexia, weight loss.

Increased ALP and GGT.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Hilar/Extrahepatic CCA Presentation

A

Jaundice

Pruritis

Anorexia, malaise, weight loss

ALP, GGT >> ALT, AST

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Endoscopic Ultrasound (EUS)

A

A great diagnostic imaging test, however may not be as readily available. Can image the entire pancreas, apulla, gall bladder.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Surgical Approach to Pancreatic Cancer

A

An R0 resection must be achieved to confer any survival benefit. This means aiming for at least a 1cm clear margin from the growth. It is hard to resect at this area without causing critical and lethal damage to nearby structures.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Recurrence Rate After Resection

A

Unfortunately, still very high even with an R0 resection.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Presentation for Pancreatic or Gall Bladder Cancer

A

Painless jaundice with weight loss are the ominous signs.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly