Asthma therapy Flashcards
1
Q
Name 2 glucocorticoids
A
Prednisolone
Budesonide
2
Q
How to glucocorticoids work?
A
Act by regulating gene transcription
- inhibit cytokine transcription
- inhibit inflammatory leukocyte migration
3
Q
Name 2 leukotriene receptor antagonists
A
Montelukast
Zafirlukast
4
Q
Name 1 leukotriene synthesis inhibitor
A
Zileuton
5
Q
What do mast cell stabilisers do?
A
Inhibit mediator release from lung mast cells
6
Q
Name 3 H1 receptor antagonists
A
Chlorpheniramine
Astemizole
Cetirizine
7
Q
What is Omalizumab?
A
Anti-IgE antibody. A monoclonal antibody
8
Q
What does omalizumab do?
A
Binds Fc portion of IgE and prevents it binding to mast cells
