Arthritis

Question 1

Septic

Answer 1

Can be native or prosthetic
Organisms via haematogenous or trauma
Native causes= h influenzae, s aureus, strep, neisseria
Prosthetic causes= s aureus, coag -ve staph, strep, anaerobes, enterococci

Question 2

Rheumatoid

Answer 2

Non-suppurative synovitis
Joints stiff in morning
Causes= genetics, AI, viruses
Tested with RF and anti-CCP

Question 3

Osteo

Answer 3

Bony spurs and cysts
Idiopathic, overuse, DM or obesity
Get heberden’s and bouchard’s nodes
Chondrocytes make IL-1 which breaks down ECM

Question 4

Sero-Negative

Answer 4

Ankylosing spondylitis
Reiter’s Syndrome
Psoriasis
Enteropathic (IBD)

Question 5

Gout

Answer 5

Too uric acid (in purine metabolism)