Aileen Giardiasis

Question 1

What type of zoonosis is giardiasis?

Answer 1

Water-borne, endemic, and Anthropozoonotic

Question 2

What is the name of the pathogen that causes giardiasis?

Answer 2

Species: Giardia intestinalis: Protozoan

Question 3

What is the taxonomy of giardiasis?

Answer 3

Genus: Giardia
Species: Giardia intestinalis

Question 4

What serovars etc are there for giardiasis?

Answer 4

Assemblages: 1-g: based on glutamate dehydrongenase gene, small unit RNA, and triophosphate isomerase genes.

Question 5

What is the morphology of giardiasis?

Answer 5

Trophozoite: 7-12 um. 2 nuclei, 8 tumbling flagella. Lg ventral sucking disc Cyst: 14x10 um. 4 nuclei. Produce two trophozoites Metabolism: glycolysis and argine dihdrolase pathway Nuleic acid: cant synthesise its own nucleic acid Mitosome: like a mitochondira contains iron-sulphate compiounds

Question 6

Is girdiasis mobile?

Answer 6

In the trophozoite stage 8 flagella

Question 7

Can giardiasis form spores?

Answer 7

encysts with 4 nuclei: The infective stage.

Question 8

how long can giardiais survive?

Answer 8

8C: 2month 21C: 1 month and Freezing

Question 9

What is the fatality of giardiasis?

Answer 9

20% of the naive population

Question 10

What is the life cycle of giardiasis?

Answer 10

Ingest spore –> excystation –> a sexual reproduction –> symptoms begin –> encytation –> cycst and trophozoite released into environment –> only cyct survive –> ingest

Question 11

What is the infection route?

Answer 11

Damage to the intestines: leads to malabsorption and damage to cells and tissue

Question 12

What is the history of giardiasis?

Answer 12

1681: Van Leeuenhook: First observed the giardia trophozoite from his oiwn shite
1881: Vilem Lambl: described giardia

1960: First Cultured
1970: Confirmed the pathogen from an outbreak of travellers of Russia

1998: USA Navel ship >100affected: Indonesia port