AAMC FL4 C/P Flashcards

1
Q

period vs frequency

A

Frequency → cycles per second

Period → seconds per cycle

frequency = 1 / period or period = 1 / frequency

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2
Q

phase diagram

A
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3
Q

how are photon energy and wavelength related?

A

energy of photon is inversely proportional to wavelength

High energy photon = low wavelength

Low energy photon = large wavelength

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4
Q

light refraction

A

the redirection of a wave as it passes from one medium to another

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5
Q

polarization of light

A
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6
Q

light diffraction

A

bending of waves around the corners of an obstacle

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7
Q

β- decay vs β+ decay

A
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8
Q

alpha decay

A
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9
Q

electron capture (type of decay)

A
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10
Q

gamma (γ) decay

A
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11
Q

conductors, resistors, and insulators

A

conductors → allow current to EASILY flow

resistors → can conduct electricity, but SLOW the current flow

insulator → allows NO current flow

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12
Q

mixed inhibition vs noncompetitive inhibition

A

the inhibitor may bind to the enzyme whether or not the enzyme has already bound the substrate but has a greater affinity for one state or the other

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13
Q

enzymes can bind to substrates in which 3 ways:

A

sequential → ordered or random

nonsequential → ping-pong (double-displacement)

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14
Q

ping-pong enzyme/substrate binding

A

the first substrate binds and is converted to a product, resulting in an intermediate enzyme form

the second substrate will then bind and be converted to product, and the enzyme will return to its original state

NO ternary complex is formed (enzyme bound to 2 substrate simultaneously)

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15
Q

ordered enzyme/substrate binding

A

one particular substrate has to bind to the enzyme first, followed by the other substrate

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16
Q

random enzyme/substrate binding

A

there is no preferred order for substrates binding to the enzyme

17
Q

ternary complex (enzymes)

A

an enzyme bound to TWO substrates (3 proteins total)

this is only formed for ordered and random mechanisms, NOT ping-pong which binds one at a time

18
Q

nucleophiles are typically _______ and function to _______

A

electron rich; form covalent bonds

19
Q

nucleophilic attack

A

the atom which the nucleophile attacks is the atom it will form a bond with

another group (the leaving group) will have to be kicked off

20
Q

catalytic efficiency

A

kcat / km

measures how well an enzyme can bind to its substrate and turn it into product

21
Q

kcat (enzyme kinetics)

A

this is the turnover number

describes how many substrate molecules are transformed into products per unit time by a single enzyme

Kcat = vmax / [E]

higher kcat = more reactions per second

22
Q

km (michaelis constant)

A

the concentration of a given enzyme that catalyzes the associated reaction at half the maximum rate (Vmax)

high Km= low affinity for its substrate

low km = high affinity for its substrate

23
Q

v max

A

the maximum velocity of an enzymatically catalyzed reaction when the enzyme is saturated with its substrate

24
Q

hydrogen bonds between base pairs

A
25
Q

amide vs amine

A
26
Q

imine

A
27
Q

Beer’s Law

A

A = elC

absorbance = (molar absorptivity) x (path length) x (concentration)