6.7 Flashcards
mutations
changes in genetic makeup and nucleotide sequence
base pair substitutions
one base pair is replaced with different pair of nucleotides
silent mutation
no effect if base pair transforms into another that signals for sasme amino acid
insertion and deletion
occurs when nucleotides are added or removed from DNA sequence, changes all codons that follow, alters protein so it is unable to perform normal functions
frameshift mutation
number of inserted/deleted nucleotides not multiple of 3
miss sense mutation
results in different amino acids (substitution)
nonsense mutation
results in STOP codon, causes translation to terminate
point mutation
change in a single nucleotide
mutagens
physical/chemical agents that interact with DNA and can cause a mutation
domains
discrete structural and functional regions of proteins
mutations increase
genetic diversity
genetic recombination
combining of DNA from 2 sources- recombinant, horizontal gene transfer
transformation
genotype and phenotype of prokaryotic cell are altered by foreign DNA
transduction
phages carry prokaryotic genes from one host cell to another
conjugation
DNA is transferred between 2 prokaryotic cells that are temporarily joined