5. Immunopathology

Question 1

antigen

Answer 1

toxin or foreign substance that induces an immune response in the body

Question 2

antibody

Answer 2

a blood protein hat is produced in response to counteracting a specific antigen

Question 3

plasma cell

Answer 3

WBC that produces a single type of antibody

Question 4

immune complex

Answer 4

when a antibody binds to an antigen, it elicits an immune response to fight off the infection/disease

Question 5

opsonisation

Answer 5

process where opsonins make the invading microorganism more susceptible to phagocytosis

Question 6

examples of external barriers

Answer 6

skin, cilia, mucous, ear wax etc

Question 7

examples of internal barriers

Answer 7

inflammation, complement, phagocytes, interferons, NKC etc

Question 8

specific immunity

Answer 8

creates memories

Question 9

roles in specific immunity: lymphoid organs

Answer 9

primary (thymus and bone marrow) and peripheral (spleen, tonsils, lymphatic system, adenoids etc)
B and T cells are produced here before they migrate toe h peripheral lymphoid organs

Question 10

where are B and T cells originate and mature?

Answer 10

both originate in the bone marrow
B cells stay and mature in bone marrow
T cells mature in the thymus

Question 11

roles in specific immunity: macrophages

Answer 11

process and present antigen to T cells

Question 12

roles in specific immunity: antibodies

Answer 12

(immunoglobulins)

synthesised and produced by plasma cells

Question 13

IgA

Answer 13

secreted in breast milk, mucus, tears, and other body secretions

Question 14

IgE

Answer 14

bind specifically to mast cells

Question 15

IgG

Answer 15

crosses the placenta, characteristics of seocndary immune response

Question 16

IgM

Answer 16

characteristic of primary Ab immune response

Question 17

IgD (just know that there is one)

Answer 17

lololol nothing GO BLUE

Question 18

histocompatibility

Answer 18

important in transplantation, immune responses and disease susceptibility/protein

Question 19

what classes of MHC are found where

Answer 19

class I MHC - all cells
class II MHC - phagocytes

Question 20

humoral immune response (antibody mediated)

Answer 20

final product is MAC (membrane attack complex)

Question 21

cell mediated immune response

Answer 21

kills off virally infected cells and cancer cells

cytotoxic t cells, NK cells and macrophages

Question 22

hypersensitivity reactions: type 1

Answer 22

immediate, allergic reactions (anaphyaxis)

Question 23

hypersensitivity reactions: type 2

Answer 23

Ab-dependent cytotoxicity and or complement dependent cytotoxicity

Question 24

hypersensitivity reactions: type 3

Answer 24

immune complex (rheumatoid arthritis)

Question 25

hypersensitivity reactions: type 4

Answer 25

cell mediated, delayed