3. Chronic Inflammation

Question 1

sequels to acute inflammation - resolution

Answer 1

the tissue reverts both structurally and functionally back to previous uninjured state (small injury = high chance of resolution)

Question 2

sequels to acute inflammation - suppuration

Answer 2

formation of pus –> adhesions/abscesses

Question 3

abscess

Answer 3

localised suppuration/pus, designed to locatalise bacterial infection and stop it from spreading

Question 4

what is a abscess comprised of?

Answer 4

scar tissue (produced by fibroblasts)
wall contains 2 layers:
1. scar tissue
2. granulation tissue

Question 5

why does chronic inflammation occur? (3)

Answer 5

1. following acute inflammation
2. repeated bouts of acute inflammation
3. from onset (usually viruses)

Question 6

cells and characteristics of chronic inflammation (4)

Answer 6

1. mononuclear cells (lymphocytes and macrophages - long-life cells)
2. fibroblasts and endothelial cells (blood vessel for granulation tissue)
3. fibroblasts (increased collagen production leading to scar formation [fibrosis])
4. low grade tissue destruction