21. Joint Disease

Question 1

synovial membrane function (3)

Answer 1

1. lubrication
2. shock absorption
3. nutrients

Question 2

articular cartilage functions

Answer 2

1. smoothness
2. protection
3. shock absorption

Question 3

aetiology of osteoarthritis (5)

Answer 3

1. overweight
2. chronic injury to the joint
3. genetics
4. impulse loading
5. joint flexibility

Question 4

pathogenesis of OA (7)

Answer 4

1. impulse loading
2. trabecular micro-fracture
3. healing
4. bone stiffening
5. stress on cartilage
6. cartilage breakdown
7. joint degeneration

Question 5

what happens in OA?

Answer 5

1. loss of cartilage
2. cartilage breaking off and lodging in synovial membrane
3. bony spurs/osteophytes
4. splitting of the cartilage

Question 6

aetiology of RA

Answer 6

idiopathic

Question 7

epidemiology of RA

Answer 7

females

Question 8

pannus

Answer 8

hyperplastic synovium

Question 9

pathogenesis of RA

Answer 9

type IV hypersensitivity and Type III hypersensitivity

rheumatoid factor IgM-IgG