3rd LEs Flashcards
(32 cards)
Structure of TAGs
3 fatty acid chain with glycerol as the backbone
Structure of waxes
Esters of fatty acids with higher molecular weight monohydric alcohol
Process of synthesis of TAGs and Waxes
Dehydration
Removed in the process of dehydration and formation of ester bonds in TAGs
3 water moelcules
Removed in the formation of waxes
1 water molecule
Structure of a glycerolphospholipid
FA + Glycerol + PX
Also known as cephalin found in cell membrane
Phospathidylethanolamine
Also known as lecithin
Phosphatidylcholine
Most abundant phospholipid of the cell membrane
Phosphatidylcholine
major component of pulmonary surfactant, composed of two palmitic acids
Dipalmitoyl lecithin
Precursor of phosphatidylinositol 4,5 bisphosphate (important cell membrane consituent) and diaculglycerol and insitol triphosphate (2nd messengers)
Phosphatidylinositol
Precurosis of cardiolipin, found only in the mitochondira
Phosphatidylglycerol
Structure of sphingolipids
FA + Sphingosine + P
composition of ceramide
Sphingosine + FA
Structure of sphingomylein
Ceramide + phosphoric acid + choline
Structure of glycolipid
FA + OH + CHO (sugar)
Location, enzyme, and deficiency of B-glucocerebroside
Liver and Spleen
B-glucosidase or glucocerebrosidase
Gaucher’s disease
Location, enzyme, and deficiency of B-galactocerebroside
Brain and myelin sheath
B-galactosidase
Krabbe’s disease
GM3
Glucose is attached to ceramide and galactose is attached to sialic acid
Gm2
GM3 + 4th cardbon of galactose is attached to another sugar and GalNac
Gm1
Gm2 + 3rd carbon of galnac is attached to galactose
A ganglioside known to be a receptor in human intestine for cholera toxin
gm3
Gangliosidosis
deficient in gm3-b-galactosidase (cleaves galactos)
Tay Sach’s disease
Deficient in hexosaminidase A (cleaves GalNac)
