3.2 Lipid Digestion and Absorption Flashcards
Where digestion of lipid begins
Stomach
Catalyzes the digestion of lipids in the stomach
Lingual lipase and gastric lipase
Emulsification of dietary lipid occurs in the
Duedenum
Structure of bile salts
sterol ring with side chain to which glycine or taurine attaches by an amide linkage
Action of pancreatic lipase
Removes FA of TAGs at carbons 1 and 3
hydorylzes cholesterul esters to produce free cholesterol plus free fatty acids
Cholesteryl ester hydrolase
Phospholipid degradation: removes fatty acid at carbon 2, leaving a lysophospholipid
Phospholipase A2
Phospholipid degradation: removes fatty acid at carbon 1, leaving a glycerolphosphoryl base
Lysophospholipase
Action of cholecystokinin
Acts on glalbladder to release bile
Acts on pancreas to release digestive enzymes
Decrease gastric motility
Activated in response to lipids and partially digested proteins entering the upper regions of the small intestine
Action of secretin
In response to low pH, causes the pancreas and liver to release a solution rich in HCO3 to neutralize pH in order to favor digestion
Activates long chain FAs to become Fatty Acyl CoA to prepare for resynthesis
Fatty Acyl Coa Synthetase
Creates TAG from Fattyl Acyl CoA and 2-monoacyl glycerol by transferring 2 fatty acids to 2-monoacyl glycerol
TAG synthase
Reacylates llysophospholipids to form phospholipid
Acyltransferase
Degrades TAG into free fatty acids and glycerol
Lipoprotein Lipase