2.7 Glycogen Metabolism

Question 1

Glycogen is a branched polymer of

Answer 1

alpha-D-glucose

Question 2

Glycogen is found at

Answer 2

Liver and muscle

Question 3

Glycogen are linked via

Answer 3

alpha-1,4 glycosidic bondbranched at 1,6 glycosidic branch every 4th residue

Question 4

Critical source of blood glucose in the postabsorptive state

Answer 4

Liver glycogen

Question 5

Storage life of glycogen

Answer 5

12-24 hours during fasting

Question 6

Muscle glycogen is a readily available source of ___ for glycolysis within the muscle itself

Answer 6

Glucose 1-phosphate

Question 7

Site of glycogen synthesis

Answer 7

Cytosol in muscle nad liver

Question 8

Rate-limiting enzyme in glycogenesis

Answer 8

Glycogen synthase

Question 9

Active form of glycogen

Answer 9

Glycogen synthase a; dephosphorylated

Question 10

Inactive form of glycogen

Answer 10

Glycogen synthase b; phosphorylated

Question 11

Regulatory kinase of glycogen synthase (inactivation)

Answer 11

Glycogen synthase kinase

Question 12

Activated by insulin; activates glycogen synthase by removing the phsphoryl groups from the 3 serine residues

Answer 12

Phosphorylase phosphatase (PPI)

Question 13

Regulatory enzyme of glycogenesis

Answer 13

Glycogen synthase

Question 14

Regulatory enzyme of glycogenolysis

Answer 14

Glycogen phosphorylase

Question 15

Initiate glycogen synthesis

Answer 15

Protein phosphatase I