2.4 Hexoses

Question 1

First irreversible reaction in glycolysis

Answer 1

Phosphorylation of glucose

Question 2

Significance of high km in glucokinas

Answer 2

High km of glucokinase means that glucolinase only becomes metabolically important when glucose levels are high

Question 3

This step in glycolysis commits glucose to metabolism

Answer 3

Phosphorylation of glucose

Question 4

2nd irreversible reaction in glycolysisAlso the 1st committed step

Answer 4

Phosphorylation of fructose 6 phosphate

Question 5

Cleaves fructose 1,6 biphosphate

Answer 5

Aldolase a

Question 6

Products of the cleavage kf fructose 1,6 biphosphate

Answer 6

Gadp and dhap

Question 7

Cleaves fructose 1phosphate onto gkyceralsehyde and dhap

Answer 7

Aldolase b

Question 8

Enzyme that drives the interconversion if gadp and dhap

Answer 8

Triose phosphate isomerase

Question 9

Enzyme for isomerization of G6P

Answer 9

Phosphohexose isomerase

Question 10

Enzyme for the phosphorylation if f6p

Answer 10

Phosphofructokinase1 (PFK)

Question 11

Also Hexokinase IV

Answer 11

Glucokinase

Question 12

First step of ATP production in glycolysisAlso the break-even point of glycolysis

Answer 12

Transfer of high energy phsphate group from 1,3 biphosphoglycerate to form 3 phosphoglycerate and ATP

Question 13

Enzyme in the first step of ATP production in glycolysis

Answer 13

Phosphoglycerate kinase

Question 14

This shunt bypasses an energy-generating step of glycolysis resulting in diminished ATP generation in RBCs

Answer 14

Rappaport-lueberring Shunt in RBCs

Question 15

Enzyme responsible for the production and utilization of L-lactate

Answer 15

Lactate dehydrogenase

Question 16

Converts pyruvate to ethanol

Answer 16

Pyruvate decarboxylase

Question 17

Deficient enzyme in classical galactosemia

Answer 17

Uridyltransferase

Question 18

Deficient enzyme in non-classifcal galactosemia

Answer 18

Galactokinase

Question 19

Deficient enzyme in clatose intolerance

Answer 19

B-galactosidase or lactase

Question 20

Accumulated in the case of a fatty liver

Answer 20

Fructose in diet; overproduction of pyruvate; hypertriacylglycerolemia

Question 21

Deficient enzyme in essential fructosuria

Answer 21

Hepatic fructokinase

Question 22

Deficient enzyme in herediatry fructose intolerance

Answer 22

Aldolase B