3.9 Lipoprotein Metabolism

Question 1

Where chylomicrons are assembled

Answer 1

Intestinal mucosal cells

Question 2

Apoproteins of chylomicrons

Answer 2

apoB-48, apoCII, apoE

Question 3

Apoprotein unique to chylomicrons

Answer 3

Aplipoprotein B-48

Question 4

Apoprotein found in VLDL and LDL

Answer 4

Apo b-100

Question 5

Assembly of apolipoproteins and lipid into chylomicrons requires (before transfer from ER to Golgi apparatus)

Answer 5

MTP (microsomal triacyleglycerol transfer protein)

Question 6

Chylomicrons become mature when it binds with

Answer 6

ApoE and apo-CII

Question 7

Necessary for the activation of LPL

Answer 7

ApoC-II

Question 8

Source of ApoE and Apo C-II

Answer 8

Circulating HDL

Question 9

Lipid transport protein that is required for the assembly and secretion of VLDL in the liver and chylomicrons by the intestine

Answer 9

MTP

Question 10

A cell surface receptor that recognizes the apoB-100 which is embedded in the phspholipid outer layer of LDL particles

Answer 10

LDL-receptor