1.3 Neurotransmitters

Question 1

Type of neurotransmission where cells are linked via gap junctions where changes in membrane potential are directly transmitted

Answer 1

Electrical

Question 2

Type of neurotransmission where neurotransmitters are released by presynaptic neurons to indirectly transmit changes in membrane potential

Answer 2

Chemical

Question 3

Catalyzes the synthesis of acetyl CoA

Answer 3

Choline acetyltransferase

Question 4

Ligand-gated ion channel receptor of ACH in the neuromuscular junction

Answer 4

Nicotinic ACh receptor

Question 5

ACh receptor mediated by G CHON (metabotropic receptor)

Answer 5

Muscarinic ACh receptor

Question 6

Degradation and uptake of Acetylcholine

Answer 6

Acetylcholinesterase

Question 7

Precursor of catecholamines

Answer 7

Tyrosine

Question 8

Process of synthesis of dopa, dopamine, epinephrine and norepinephrine

Answer 8

HydroxylationDecarboxylationHydroxylationMethylation

Question 9

Storage of catecholamines

Answer 9

VMAT2

Question 10

Reuptake of dopamine

Answer 10

Dopamine transporter

Question 11

Reuptake of norepinephrine

Answer 11

Norepinephrine transporter

Question 12

Degradation of dopamine and norepinpehrine via oxidative deamination

Answer 12

Monoamine Oxidase

Question 13

degradation of dopamine and norepinephrine via o-methylation

Answer 13

cathecol 0-methyl transferase

Question 14

Degeneration of dopaminergic neurons in the substantia nigra of the brain

Answer 14

Parkinson’s disease

Question 15

Autoimmune disease caused by circulating antibodies which break down cholinergic receptors

Answer 15

Myasthenia Gravis

Question 16

Precursosi of serotonin

Answer 16

Tryptophan

Question 17

Synthesis of serotonin and melatonin

Answer 17

HydroxylationDecarboxylationAcetylationMethylation

Question 18

Reuptake of serotonine

Answer 18

Serotonin transporter

Question 19

Degradation of serotonin

Answer 19

MAO, then oxidation by aldehyde dehydrogenase

Question 20

Function of glutamate

Answer 20

Excitatory neurotransmitter in the CNS

Question 21

Inactivation or dgradation of glutamate

Answer 21

taken by glial cells then converted to glutamine

Question 22

Excitatory neurotransmitter that cannot pass through blood brain barrier

Answer 22

Aspartate

Question 23

Major inhibitory neurotransmitter in the brainstem and spinal cord

Answer 23

Glycine

Question 24

Precursor of glycine

Answer 24

Serine

Question 25

Major inhibitory neurotransmitter in the brain

Answer 25

GABA

Question 26

Precursor of GABA

Answer 26

Glutamate

Question 27

Inactivation of GABA

Answer 27

glial cells then converted to glutamate which is then converted to glutamine