3.2 Lipid Digestion And Absoprtion Flashcards
Stomach digestion of lipids is catalyzed by
Lingual lipase
Gastric lipase
Digestion of lipids starts in the
Stomach
Gastric lipase removes fatty acids located at
Carbon 1 and 3
Product of gastric lipase
2-monoacylglycerol
Site of lipid emulsification
Duodenum
Produces bile salts
Liver
Stores bile salts
Gall bladder
Cholesterol derivatives consist of a
Sterol ring with glycine or taurine
Are emulsifying agents which stabilize the dietary lipid particles as they become smaller and prevent them from coalescing
Bile salts
Acts upon TAG molecules which are too large to be taken up efficiently by mucosal cells of the intestinal villi
Pancreatic lipase
Pancreatic lipase removes acids at carbon ___ using __ reactions
1 and 3
Hydrolysis
Products of hydrolysis by pancreatic lipase
2-monoacylglycerol and free fatty acids
Restores activity to lipase in the presence of inhibitory substances like bile acids that bind the micelles
Colipase
Orlistat inhibits
Gastric lipase and pancreatic lipase
Hydrolyzes cholesteryl esters to produce free cholesterol plus free fatty acids
Cholesteryl Ester Hydrolase (Cholesterol Esterase)