3.2 Lipid Digestion And Absoprtion Flashcards

0
Q

Stomach digestion of lipids is catalyzed by

A

Lingual lipase

Gastric lipase

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1
Q

Digestion of lipids starts in the

A

Stomach

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2
Q

Gastric lipase removes fatty acids located at

A

Carbon 1 and 3

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3
Q

Product of gastric lipase

A

2-monoacylglycerol

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4
Q

Site of lipid emulsification

A

Duodenum

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5
Q

Produces bile salts

A

Liver

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6
Q

Stores bile salts

A

Gall bladder

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8
Q

Cholesterol derivatives consist of a

A

Sterol ring with glycine or taurine

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9
Q

Are emulsifying agents which stabilize the dietary lipid particles as they become smaller and prevent them from coalescing

A

Bile salts

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10
Q

Acts upon TAG molecules which are too large to be taken up efficiently by mucosal cells of the intestinal villi

A

Pancreatic lipase

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11
Q

Pancreatic lipase removes acids at carbon ___ using __ reactions

A

1 and 3

Hydrolysis

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12
Q

Products of hydrolysis by pancreatic lipase

A

2-monoacylglycerol and free fatty acids

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13
Q

Restores activity to lipase in the presence of inhibitory substances like bile acids that bind the micelles

A

Colipase

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14
Q

Orlistat inhibits

A

Gastric lipase and pancreatic lipase

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15
Q

Hydrolyzes cholesteryl esters to produce free cholesterol plus free fatty acids

A

Cholesteryl Ester Hydrolase (Cholesterol Esterase)

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16
Q

Increases the activity of cholesteryl ester hydrolase (cholesteryl esterase)

A

Bile salts

17
Q

COntained in the pancreatic juice which removes one fatty acid from carbon 2 of a phospholipid

A

Phospholipase A2

18
Q

product of a phospholipase A2

A

Lysophospholipid

19
Q

Removes remaining fatty acid at carbon 1 of a phospholipid

A

Lysophosphplipase

20
Q

Product of a lysophospholipase

A

Glycerolphosphoryl base

21
Q

Small peptide hormone produced by the cells in the mucosa of lower duodenum and jejunum; formed in response to the presence of lipids and partially digested proteins entering the duodenum and jejunum

A

Cholecystokinin

22
Q

Functions of the cholecystokinin

A

Gallbladder: enables release of bile
Pancreatic: exocrine cells: release of digestive enzymes
Decrease gastric motility

23
Q

Small peptide hormone produced by the intestines in response to the low pH of the chyme entering the pH; causes the pancreas and the liver to release a solution rich in bicarbonate to neutralize pH to enhance digestive activity by pancreatic enzymes

A

Secretin

24
Q

Site of bile absorption

A

Ileum

25
Q

In order to be activated, long chain fatty acids are acted upon by the enzyme ___

A

Fatty Acyl CoA Synthetase or Thiokinase

26
Q

Product of Acyl CoA Synthetase or Thiokinase

A

Fatty Acyl CoA

27
Q

Converts fatty acyl CoA into tiracylglycerol by combining Fatty Acyl CoA with a 2-monoacyl glycerol

A

TAG Synthase (Monoacylglycerol Acyltransferase and Diacylglycerol Acyltransferase)

28
Q

Catalyzes the formation of Cholesteryl ester from fatty acyl CoA

A

Acyl CoA: Cholesterol Acyltransferase

29
Q

Lymph with exocytosed particles

A

Chyle

30
Q

Particles inside the lumph

A

Chylomicrons

31
Q

Degrades TAG into free fatty acids and glycerol

A

Lipoprotein lipase