3.4.3 Diabetes Mellitus and Treatment Flashcards
What are the effects of GLP-1?
What is the treatment algorithm for type 2 DM?
What are the treatment goals of Type I DM?
What are some of the different insulin preparations?
What are some of the symptroms of hypoglycemia?
What treatment method is on the horizon for Type 1 DM?
Closed loop pumps
What is the mainstay for the treatment of Type 1 DM?
Insulin injection
What are the four types of neuropathy possible in DM patients?
Peripheral, autonomic, proximal, focal
What are some of the oral anti-hyerglycemics and their attributes
What two lifestyle changes help in the preservation of islet beta cells?
Diet and Excercise
What are the treatment goals of type 2 DM?
What is the progression of treatment of Type 2 DM?
How do thiazolidinediones decrease insulin resistance?
Make muscle and adipose cells more sensitive to insulin
What are two retinopathies associated with DM?
Proliferative retinopathy, macular edema
What type of DM predisposes patients to hyperosmolar hyperglycemic state?
Type II DM
Identify the drugs in these classes?
What is the normal insulin excretion style?
Pulsatile
What is increased by sulfonylurea?
Endogenous insulin secretion
What are some of the future changes in the treatment of DM?
Preservation/regeneration of islet cells
Stop immune destruction
Islet cell transplantation
Closed loop insulin pumps
Better insulin
Stop obesity
What are some of the Type 1 DM management goals?
Normalize glucose, BP and lipid management to reduve CVD
What type of DM predisposes patients to DKA?
Type I DM
What is the function of the enzymes that are blocked by alpha-glucocidase inhibitors?
Digest starches in the small intestine
What are some of the complications of DM?
Atherosclerosis, retinopathy, neuropathy, nephropathy, hypoglycemia unawareness, diabetic foot, DKA, hyperosmolar nonketotic coma, HOHG
How does Ashley feel about this lecture?
Unamused
