3.4.3 Diabetes Mellitus and Treatment

Question 1

What are the effects of GLP-1?

Answer 1

Question 2

What is the treatment algorithm for type 2 DM?

Answer 2

Question 3

What are the treatment goals of Type I DM?

Answer 3

Question 4

What are some of the different insulin preparations?

Answer 4

Question 5

What are some of the symptroms of hypoglycemia?

Answer 5

Question 6

What treatment method is on the horizon for Type 1 DM?

Answer 6

Closed loop pumps

Question 7

What is the mainstay for the treatment of Type 1 DM?

Answer 7

Insulin injection

Question 8

What are the four types of neuropathy possible in DM patients?

Answer 8

Peripheral, autonomic, proximal, focal

Question 9

What are some of the oral anti-hyerglycemics and their attributes

Answer 9

Question 10

What two lifestyle changes help in the preservation of islet beta cells?

Answer 10

Diet and Excercise

Question 11

What are the treatment goals of type 2 DM?

Answer 11

Question 12

What is the progression of treatment of Type 2 DM?

Answer 12

Question 13

How do thiazolidinediones decrease insulin resistance?

Answer 13

Make muscle and adipose cells more sensitive to insulin

Question 14

What are two retinopathies associated with DM?

Answer 14

Proliferative retinopathy, macular edema

Question 15

What type of DM predisposes patients to hyperosmolar hyperglycemic state?

Answer 15

Type II DM

Question 16

Identify the drugs in these classes?

Answer 16

Question 17

What is the normal insulin excretion style?

Answer 17

Pulsatile

Question 18

What is increased by sulfonylurea?

Answer 18

Endogenous insulin secretion

Question 19

What are some of the future changes in the treatment of DM?

Answer 19

Preservation/regeneration of islet cells

Stop immune destruction

Islet cell transplantation

Closed loop insulin pumps

Better insulin

Stop obesity

Question 20

What are some of the Type 1 DM management goals?

Answer 20

Normalize glucose, BP and lipid management to reduve CVD

Question 21

What type of DM predisposes patients to DKA?

Answer 21

Type I DM

Question 22

What is the function of the enzymes that are blocked by alpha-glucocidase inhibitors?

Answer 22

Digest starches in the small intestine

Question 23

What are some of the complications of DM?

Answer 23

Atherosclerosis, retinopathy, neuropathy, nephropathy, hypoglycemia unawareness, diabetic foot, DKA, hyperosmolar nonketotic coma, HOHG

Question 24

How does Ashley feel about this lecture?

Answer 24

Unamused