2do examen infectologia Rabia Flashcards

1
Q

Caracteristicas del virus de la rabia

A

ARN, lyssavirus, envuelto, forma de proyectil, zoonotica

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2
Q

Reservorios del virus de la rabia

A

Perros, gatos, murcielagos, mapaches, lobos, zorros

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3
Q

Medios de ciclo de transmision de la rabia

A

Silvestre, urbano, rural y aereo

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4
Q

Patogenia de la rabia

A

El virus adentra la piel y se aloja en los miocitos
Por medio del SNP llega al SNC
Astas de ammon en el hipocampo
Neuronas de purkinje
Forma los corpusculos de Negri

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5
Q

Al llegar en el SNC que organos va afectar

A

Retina
Corteza adrenal
Glandulas salivares
Riñon
Corazon

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6
Q

Cuadro clinico de la rabia

A

Incubacion (20 a 60 d)
Prodromico (2 a 10 d)
Excitacion (24 a 72 h)
Coma (24h) Paralisis flacida generalizada y muerte

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7
Q

Caracteristicas del prodromo de la rabia

A

Parestesias
Dolor local
Tumefaccion
Fiebre
Mialgia, altralgia

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8
Q

Caracteristicas de la fase de excitación de la rabia

A

Alteraciones sensitivas, motoras y psiquicas
Excitacion simpatica
Espasmos faringeos
Furia
Agitacion psicomotriz
Alucinaciones

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9
Q

Diagnostico de la rabia

A

Post Mortem
Biopsia de piel, cornea, LCR, saliva, astas de ammon
INMUNOFLUORESCENCIA

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10
Q

Conducta terapeutica de la rabia

A

Vacuna de cultivos celulares
Vacunas Fuenzalida y Palacios (paises subdesarrolados)
Gammaglobulina antirrabica (homologo 20ui/kg o heterologo 40ui/kg)

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11
Q

Esquema vacunación post exposición

A

1 dosis al dia 0-3-7-14-28 (5 dosis)

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12
Q

Esquema vacunación preexposición

A

1 dosis dia 0 - 7 - 28 - al año

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