26 Smertebehandling av opioidavhengige Flashcards

1
Q

smerteanamnesen

A

LDAVKVU LNFL

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2
Q

typer smerte

A

nociseptive smerter = somatiske og viscerale, kroppsvev

nevropatiske smerter = skade i nervefiberet

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3
Q

smertedebut

A

akutt vs kronisk

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4
Q

smerte er et __ fenomen

A

komplekst

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5
Q

smertetrappa trinn 1

A

NRS 1-3 = paracetamol el NSAID

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6
Q

smertetrappa trinn 2

A

NRS 4-7 = paracetamol el NSAID + svakt opioid

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7
Q

smertetrappa trinn 3

A

NRS 8-10 = paracetamol el NSAID + sterkt opioid

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8
Q

opioid hyperalgesi

A

paradoksal overfølsomhet for smerte, utvikles parallelt med opioidtoleranse

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9
Q

toleranseutvikling

A

opioidtolerante pasienter vil oppleve smerter som om de ikke brukte opioider

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10
Q

opioider virker perifert mens paracetamol og NSAIDs virker sentralt og perifert

A

omvendt

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11
Q

buprenorfin og metadon er __

A

sterke opioider

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12
Q

dosering buprenorfin og metadon

A
buprenorfin = 0.8 - 1.2 mg x 3-4 per døgn
metadon = 10-20 mg x 3-4 per døgn
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13
Q

opioidavhengige behøver …

A

… større dosering av buprenorfin og metadon for adekvat smertelindring

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14
Q

substituttbeh hos opioidavhengige

A

buprenorfin 8-16 mg per døgn
metadon 50-100 mg per døgn
illegal heroin opptil 2g iv per døgn

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15
Q

opioidtilvendte vs opioidnaive

A

brukt opioider tidl ?

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16
Q

mimikk …

A

vil oftest avsløre smerter