2.3-LipidDigestion&Absorption Flashcards
What type of lipid makes 90% of our dietary lipids??
TriAcylGlycerols!
What are the two essential Fatty Acids? What are their omega types?
LIN-OLE-IC (Omega 6) & LIN-OLE-N-IC (Omega 3) add an N equals 3?
Where are the three lipid enzymes made in the body?
The Pancreas
What are the three main lipid enzymes we discussed?
Cholesterol Esterase, Lipase, Pancreatic Lipase
What enzyme is released to begin emulsification in the mouth with ingested phospholipids? What is a source of phospholipids? Does this lipid hydrolysis happen often in adults?
Lingual Lipase. Cells that you eat. No it does not happen often in adults in mouth or stomach.
What are the two lipid enzymes in the stomach? What is the optimal pH?
Acid-Stable(Lingual) Lipase & Gastric Lipase-only works at pH of 7. Only babies have a pH of 7 in the stomach
What turns macroscopic fat particles into microscopic drops? What are the microscopic droplets called?
Bile Salts break up the big particles. Micelles.
Where are bile salts made? Where are they stored?
Made in the liver, stored in the gallbladder
What are bile salts derived from? What are the two conjugates?
Derived from cholesterol(cholic acid). Conjugates of Glycene (Glycocholic Acid) and Taurine (Taurocholic Acid)
What is the name of the cycle in which bile salts are made in the liver, used in the s.i., and then returned to the liver?
ENTERO-HEPATIC Cycle
What hormone stimulates gallbladder bile release, pancreatic enzyme release, slow of gastric emptying, and tells the brain its full?
CHOLE-CYSTO-KININ (CCK y’all)
What is the hormone that helps neutralize the pH of the stomach to the s.i.? Where is it released? What does it tell the pancreas to do?
SECRETIN- Release from the Doudenum- tells the pancreas to release BiCarb
What was the first hormone ever identified in 1902?
Secretin
Which pancreatic enzyme takes TriAcylGlycerols to MonoAcylGlycerols?
Pancreatic Lipase
Which pancreatic enzyme breaks down cholesterol esters to free fatty acids and cholesterol?
Cholesteryl Esterase.. Crazy name, I know
Which pancreatic enzyme removes fatty acids from phospholipids?
PhosphoLipase A2. Wow, another crazy ass name
Which pancreatic enzyme works best at the Interfacial Activation? What is it stabilized with?
Pancreatic Lipase..Stabilized with CoLipase
What is the origin of the CoLipase? What is it cleaved by? What is the other 5 AA signaler??
Origin: ProCoLipase Cleaved by: Trypsin Other 5AA product: ENTERO-STATIN
What is the function of EnteroStatin?
Satiety! Where can I get some of that!!
Is the reaction for converting cholesterol ester to cholesterol very efficient? Do we really need to absorb cholesterol?
Cholesteryl Esterase is not a very efficient reaction. Don;t care because our liver synthesizes the cholesterol we need!
What are the two enzymes activated by Trypsin?
ProCoLipase & PhosphoLipase A2
Which enzyme removes a fatty acid at C2 of a phospholipid and turns it into a lysophospholipid?
PhosphoLipase A2
Which enzyme is involved in Bee and Snake venom?
Phospholipase A2
Which enzyme removes the remaining fatty acid from lysophospholipid?
LysoPhosphoLipase. ANOTHER CRAZY NAME :)
