[16] Citric Acid Cycle Flashcards

1
Q

What is the Citric Acid Cycle?

A

A series of chemical reactions used by all aerobic organisms to release stored energy.

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2
Q

Where does the Citric Acid Cycle occur in the cell?

A

In the mitochondrial matrix.

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3
Q

What is the starting molecule for the Citric Acid Cycle?

A

Acetyl-CoA.

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4
Q

How many molecules of carbon dioxide are produced per turn of the Citric Acid Cycle?

A

Two CO2 molecules.

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5
Q

What is the end product of the Citric Acid Cycle?

A

Oxaloacetate.

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6
Q

How many ATP molecules are produced in the Citric Acid Cycle?

A

One ATP (or GTP).

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7
Q

What are the main products of the Citric Acid Cycle?

A
  • ATP/GTP
  • NADH
  • FADH2
  • CO2
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8
Q

What is the significance of NADH and FADH2 produced in the Citric Acid Cycle?

A

They are used in the Electron Transport Chain to produce ATP.

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9
Q

How many NADH are produced per cycle?

A

Three NADH.

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10
Q

How many FADH2 are produced per cycle?

A

One FADH2.

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11
Q

How many cycles does one glucose molecule go through?

A

Two cycles (as glucose is split into two pyruvate molecules during glycolysis).

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12
Q

What are the main regulatory enzymes in the Citric Acid Cycle?

A
  • Citrate synthase
  • Isocitrate dehydrogenase
  • Alpha-ketoglutarate dehydrogenase
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13
Q

What is the role of Coenzyme A in the Citric Acid Cycle?

A

It transports the acetyl group to the cycle.

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14
Q

What is the role of oxaloacetate in the Citric Acid Cycle?

A

It combines with acetyl-CoA to form citrate, starting the cycle.

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15
Q

What molecule does citrate synthase produce?

A

Citrate.

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16
Q

What molecule does isocitrate dehydrogenase produce?

A

Alpha-ketoglutarate.

17
Q

What molecule does alpha-ketoglutarate dehydrogenase produce?

A

Succinyl-CoA.

18
Q

What happens to the carbon atoms in the acetyl group of acetyl-CoA during the Citric Acid Cycle?

A

They are oxidized to CO2.

19
Q

What is the role of the Citric Acid Cycle in the metabolism of proteins, carbohydrates, and fats?

A

It is the common final pathway for the oxidation of fuel molecule fragments.

20
Q

What happens to NADH and FADH2 after the Citric Acid Cycle?

A

They enter the Electron Transport Chain to generate ATP.