[03] Amino Acids, Peptides, and Proteins Flashcards

1
Q

What are amino acids?

A

Organic molecules that serve as the building blocks for proteins.

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2
Q

How many common amino acids are there?

A

20

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3
Q

What are the three key elements of an amino acid structure?

A
  • Amino group (-NH2)
  • Carboxyl group (-COOH)
  • Side chain (R group)
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4
Q

How are amino acids classified?

A

Based on the properties of their side chains: nonpolar, polar but uncharged, positively charged, and negatively charged.

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5
Q

Give examples of nonpolar amino acids.

A
  • Glycine (Gly)
  • Alanine (Ala)
  • Valine (Val)
  • Leucine (Leu)
  • Isoleucine (Ile)
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6
Q

Gly - Initials

A

Glycine

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7
Q

Ala - Initials

A

Alanine

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8
Q

Val - Initials

A

Valine

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9
Q

Leu - Initials

A

Leucine

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10
Q

Ile - Initials

A

Isoleucine

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11
Q

What is a peptide bond?

A

A covalent bond formed between two amino acids when the carboxyl group of one reacts with the amino group of another, releasing a molecule of water.

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12
Q

What is a peptide?

A

A molecule consisting of two or more amino acids linked by peptide bonds.

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13
Q

What is a protein?

A

A large molecule composed of one or more chains of amino acids in a specific order; the order is determined by the base sequence of nucleotides in the gene that codes for the protein.

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14
Q

What determines the function of a protein?

A

Its shape and structure, which is primarily determined by its amino acid sequence.

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15
Q

What are the four levels of protein structure?

A
  • Primary structure
  • Secondary structure
  • Tertiary structure
  • Quaternary structure
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16
Q

Define the primary structure of a protein.

A

The sequence of amino acids in a protein; it dictates the protein’s higher-level structures and function.

17
Q

What are the two types of secondary protein structure?

A

Alpha helix and beta sheet.

18
Q

What is the tertiary structure of a protein?

A

The three-dimensional shape of a protein, determined by interactions among various side chains (R groups) of amino acids.

19
Q

What is the quaternary structure of a protein?

A

The structure resulting from the association of two or more polypeptide chains (subunits) into one functional protein.

20
Q

How can a protein lose its function?

A

If it becomes denatured, which means its structure is altered and it loses its correct shape.