Wk 6 Antineoplastics Flashcards
0
Q
Fludarabine
A
purine analog
no DNA synthesis
S-phase specific
1
Q
Methotrexate
A
inhibits folate synthesis
inhibits DNA synthesis
S-phase specific
2
Q
Cyclophosphamide
A
alkylating agent
DNA damage
not phase specific
3
Q
Cisplatin
A
PLATnum crosslinks DNA
cell cycle nonspecific
4
Q
Doxorubicin
A
intercollates DNA
cell cycle nonspecific
5
Q
Etoposide
A
topo II inhibitor
G2/S inhibitor
6
Q
Paclitaxel
A
spindle stabilizer
M phase specific