Wk 3 Lyme Disease

Question 1

Lyme offending organism (most common)

Answer 1

Borrelia burgdorferi

Question 2

B. burgdorferi vector (most common)

Answer 2

I. scapularis

Question 3

Mean amount of time of tick attachment for reliable lyme infection

Answer 3

36 h

Question 4

I. scapularis reservoirs

Answer 4

mouse and deer

Question 5

Borrelia morphology

Answer 5

spirochaete

Question 6

3 stages of Borrelia infection

Answer 6

1. Early localized
2. Early disseminated
3. Late (persistant)

Question 7

Pt presents with AV block secondary to Borrelia infection. Who do you not let near your patient?

Answer 7

cardiothoracic surgery

Question 8

Testing for Borrelia infection: 2 step process

Answer 8

1. ELISA

2. Western blot

Question 9

What antibodies do you look for in serum tests for Borrelia infection?

Answer 9

IgG (≥2) and IgM (≥5)

Question 10

Tx of Borrelia

Answer 10

DOXY

Question 11

Doxy tastes bad, why should Santa not get Lyme disease around Christmas time?

Answer 11

because it will be kelated with his milk

Question 12

For advanced Borrelia infection, what IV antibiotic is used?

Answer 12

ceftriaxone

Question 13

Why might Lyme symptoms persist after infection has cleared?

Answer 13

permanent tissue damage, cytokine disequilibrium