Wk 6 Anti-Arthritic Drugs Flashcards by Robbie Gruhl | Brainscape

Q

Methotrexate

A

block dihydrofolate reductase

B-cells and T-cells

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Q

Hydroxychloroquine

A

prevents acidification of macrophage

APC

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Q

Leflunomide

A

blocks ororate pathway and pyrimidine synthesis

T-cells

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Q

Sulfasalazine

A

metabolites are COX antagonists

T-cell and B-cells

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Q

Gold

A

suppresses phagocytosis by macrophages

macrophages

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Q

Azathioprine

A

purine analog, blocks DNA synthesis

T-cells

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Q

Cyclosporin

A

calcineurin inhibitor on T-cells

T-cells

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Q

Etanercept and inflixumab

A

TNF inhibitors

TNF-alpha

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Q

Anakinia

A

IL-1

IL-1

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Q

Rituximab

A

CD20 inhibitors

B-cells

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Q

Abatacept

A

CD80 inhibitor

T-cells

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