Wk 3 Derm Therapeutics Flashcards
1
Q
Corticosteroids
- actions
- conditions
- adverse
A
- anti-inflammatory, antiproliferative, vasoconstrictive
- eczema, contact dermatitis, psoriasis
- skin atrophy
2
Q
Retinoids (topical–Vit A analogue)
- actions
- conditions
- adverse
A
- normalize cell growth, inhibit carcinogenesis
- acne, psoriasis, cosmetic skin improvement
- dryness, irritation, sun sensitivity
3
Q
Calcipotriene (Vit D analogue)
- actions
- conditions
- adverse
A
- alters skin differentation
- psoriasis, eczema
- irritation, hypercalcemia
4
Q
Topical calcineurin inhibitors
- actions
- conditions
- adverse
A
- alter T-cell activation
- eczema, dermatitis
- limited, local itching or burning
5
Q
Reflective agens in sunscreens
A
zinc and titanium
6
Q
SPF 30 blocks what percent of UV rays?
A
97%
7
Q
Imiquimod
- actions
- conditions
- adverse
A
- immune response modifier (increased locally)
- condyloma, actinic keratosis, basal cell carcinoma
- not listed
8
Q
Topical 5-FU
- actions
- conditions
- adverse
A
- thymidylate synthase
- actinic keratosis
- not listed
9
Q
What is the best way to dress a healing wound?
A
cover it, allowing natural cytokines to promote healing
10
Q
Retinoids (systemic–Vit A analogue)
- actions
- conditions
- adverse
A
- normalize cell growth
- psoriasis, acne
- birth defects, dryness
11
Q
Dapsone
- actions
- conditions
- adverse
A
- inhibits something
- leprosy, neutrophilic skin diseases
- hemolysis
12
Q
Methotrexate
- actions
- conditions
- adverse
A
- inhibits dihydrofolate reductase
- psoriasis, lupus
- hepatotoxicity
13
Q
Biological therapy
A
recombinant protein technology
14
Q
UV light therapy
- actions
- conditions
- adverse
A
- forms pyrimadine dimers
- psoriasis
- burns, carcinogenic
15
Q
Minoxidil
- actions
- conditions
- adverse
A
- vasodialation around hair shaft
- alopecia
- not listed