Wk 3 Derm Therapeutics Flashcards

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1
Q

Corticosteroids

  • actions
  • conditions
  • adverse
A
  • anti-inflammatory, antiproliferative, vasoconstrictive
  • eczema, contact dermatitis, psoriasis
  • skin atrophy
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2
Q

Retinoids (topical–Vit A analogue)

  • actions
  • conditions
  • adverse
A
  • normalize cell growth, inhibit carcinogenesis
  • acne, psoriasis, cosmetic skin improvement
  • dryness, irritation, sun sensitivity
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3
Q

Calcipotriene (Vit D analogue)

  • actions
  • conditions
  • adverse
A
  • alters skin differentation
  • psoriasis, eczema
  • irritation, hypercalcemia
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4
Q

Topical calcineurin inhibitors

  • actions
  • conditions
  • adverse
A
  • alter T-cell activation
  • eczema, dermatitis
  • limited, local itching or burning
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5
Q

Reflective agens in sunscreens

A

zinc and titanium

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6
Q

SPF 30 blocks what percent of UV rays?

A

97%

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7
Q

Imiquimod

  • actions
  • conditions
  • adverse
A
  • immune response modifier (increased locally)
  • condyloma, actinic keratosis, basal cell carcinoma
  • not listed
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8
Q

Topical 5-FU

  • actions
  • conditions
  • adverse
A
  • thymidylate synthase
  • actinic keratosis
  • not listed
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9
Q

What is the best way to dress a healing wound?

A

cover it, allowing natural cytokines to promote healing

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10
Q

Retinoids (systemic–Vit A analogue)

  • actions
  • conditions
  • adverse
A
  • normalize cell growth
  • psoriasis, acne
  • birth defects, dryness
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11
Q

Dapsone

  • actions
  • conditions
  • adverse
A
  • inhibits something
  • leprosy, neutrophilic skin diseases
  • hemolysis
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12
Q

Methotrexate

  • actions
  • conditions
  • adverse
A
  • inhibits dihydrofolate reductase
  • psoriasis, lupus
  • hepatotoxicity
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13
Q

Biological therapy

A

recombinant protein technology

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14
Q

UV light therapy

  • actions
  • conditions
  • adverse
A
  • forms pyrimadine dimers
  • psoriasis
  • burns, carcinogenic
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15
Q

Minoxidil

  • actions
  • conditions
  • adverse
A
  • vasodialation around hair shaft
  • alopecia
  • not listed
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16
Q

Finasteride

  • actions
  • conditions
  • adverse
A
  • blocks testosterone degradation
  • androgenic alopecia
  • not listed
17
Q

Liquid nitrogen

  • actions
  • conditions
  • adverse
A
  • freezes tissue
  • warts, keratoses, skin tags
  • not listed
18
Q

Tinea capitis

  • organism
  • pathology
  • Tx
A
  • Trichophyton tonsurans
  • fungal growth, possible scarring
  • griseofulvin, terbinafine, itraconazole