Wk 4 Muscle Paralytics Flashcards
0
Q
Edrophonium
A
anti-AChE
used to Dx myasthenia Travis
“tensalin test”
1
Q
Pyridostigmine
A
anti-AChE
2
Q
Neostigmine
A
anti-AChE
used in hospitalized patients
3
Q
Tubocurarine
A
nAChR antagonist
prevents AP
4
Q
Mivacurarine
A
nAChR antagonist
prevents AP
5
Q
Succinylcholine
A
nAChR agonist
prolonged depolarization
may provoke malignant hyperthermia
6
Q
Botulinum toxin
A
cleaves vesiclenproteins
no ACh release
no AP
7
Q
Tetanus toxin
A
blocks inhibitory neuron glycine release
no inhibition of AP
constant contraction
8
Q
Dantrolene
A
inhibits calcium release
AP occurs but no contraction
used in malignant hyperpyrexia