Wk 4 Muscle Paralytics Flashcards

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0
Q

Edrophonium

A

anti-AChE
used to Dx myasthenia Travis
“tensalin test”

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1
Q

Pyridostigmine

A

anti-AChE

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2
Q

Neostigmine

A

anti-AChE

used in hospitalized patients

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3
Q

Tubocurarine

A

nAChR antagonist

prevents AP

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4
Q

Mivacurarine

A

nAChR antagonist

prevents AP

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5
Q

Succinylcholine

A

nAChR agonist
prolonged depolarization
may provoke malignant hyperthermia

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6
Q

Botulinum toxin

A

cleaves vesiclenproteins
no ACh release
no AP

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7
Q

Tetanus toxin

A

blocks inhibitory neuron glycine release
no inhibition of AP
constant contraction

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8
Q

Dantrolene

A

inhibits calcium release
AP occurs but no contraction
used in malignant hyperpyrexia

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