Wk 3 Acute Inflammatory Dermatosis Flashcards
Urticaria:
- presentation
- pathophys
- common name
- erythemitis pruritic wheal lesions
- IgE/histamine mediated (type I hypersensitivity)
- hives
Angioedema:
- presentation
- pathophys
- common name
- deep dermal/sub-Q burning, painful swelling
- IgE/histamine mediated (type I hypersensitivity)
- emergent allergic rxn
Two classes of urticaria causes
- immune
- nonimmune
Examples of immune urticaria
drug rxn: penicillin, sulfonamides, insect bites, etc.
food rxn: peanuts, shellfish, eggs, milk, soy, etc.
viral rxn: Hep A, B, C, Epstein-Barr, HIV, etc.
Examples of non-immune uritcaria
physical: sun, sweating, vibrations, etc.
direct mast cell degranulation: NSAIDs, dextran, vanco, etc.
First choice drug for chronic urticaria
antihistamines (cetirizine, Zyrtec)
Erythema multiforme:
- presentation
- pathophys
- erythemic target-shaped lesions on extremities, does not itch
- immune, viral, idiopathic
Viral causes of erythema multiforme
herpes simplex
Erythema multiforme can progress to what disease?
Stevens-Johnson syndrome
Stevens-Johnson syndrome
extreme erythema multiforme
Toxic epidermal necrolysis
extreme Stevens-Johnson syndrome
Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis most likely cause
Rx
Fixed drug eruption
- presentation
- pathophys
- sharply demarcated erythematous patch that may itch, burn, or be asymptomatic
- possibly immune
Panniculitis
- presentation
- pathophys
- erythematous patches in sub-Q
- meds, infection, autoimmune
Common Rx cause of panniculitis
oral contraceptives
