Week 9- Cardiovascular Disorders Flashcards
What is a cardiomyopathy?
A disorder that affects the cardiomyocytes or cardiac muscle function
What is heart failure?
Inability of the heart to maintain adequate circulation for the metabolic requirements of the body
What happens to ejection fraction during heart failure?
It can be preserved or reduced
What is preserved ejection fraction?
Heart function equal to or below 50% (reduced diastolic function-decreased muscle mass in left ventricle, can pump but can’t relax as well)
What is reduced ejection fraction?
Heart function equal to or below 40% (reduced systolic function-heart hasn’t got enough strength to pump out blood)
What type of ejection fraction causes reduced diastolic function?
Reduced ejection fraction
What type of ejection fraction causes reduced systolic function?
Preserved ejection fraction
What are causes of heart failure?
Secondary to cardiac damage eg ischaemia/myopathy, hypertension, valve disease
What type of ejection fraction does hypertension affect?
Preserved- hypertension causes thickening of the cardiac muscle wall making it harder for the muscle to relax
What happens to cardiac output during heart failure?
It falls
What are general symptoms of heart failure?
Breathlessness, fatigue, fluid retention (caused by cardiac dysfunction)
How is heart failure visible on an ECG?
Enlarged QRS complex (generally taller, can also be wider)
How is heart failure diagnosed?
Echocardiography or elevated natriuretic peptides
What is Tako Tsubo syndrome?
Left ventricular dysfunction where apex balloons and symptoms mimic MI (myocardial infarction)- also known as broken heart syndrome
What is the main cause of Tako Tsubo syndrome?
Stressful event
Who does Tako Tsubo syndrome usually affect?
Women
How does Tako Tsubo syndrome affect cardiac output?
Reduces it to around 40%
How is Tako Tsubo syndrome visible on an ECG?
ST segment elevation
What are some symptoms of Tako Tsubo syndrome?
Chest pain, increased cardiac biomarkers but blood vessels are normal
What are conduction abnormalities?
Disorders that affect bioelectrical transmission along the heart
What is dilated cardiomyopathy?
Cardiomegaly and dilation, systolic dysfunction with
hypo-contraction
What are the causes of dilated cardiomyopathy?
20-50% familial, also secondary to MI