Week 9- Cardiovascular Disorders Flashcards

1
Q

What is a cardiomyopathy?

A

A disorder that affects the cardiomyocytes or cardiac muscle function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is heart failure?

A

Inability of the heart to maintain adequate circulation for the metabolic requirements of the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What happens to ejection fraction during heart failure?

A

It can be preserved or reduced

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is preserved ejection fraction?

A

Heart function equal to or below 50% (reduced diastolic function-decreased muscle mass in left ventricle, can pump but can’t relax as well)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is reduced ejection fraction?

A

Heart function equal to or below 40% (reduced systolic function-heart hasn’t got enough strength to pump out blood)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What type of ejection fraction causes reduced diastolic function?

A

Reduced ejection fraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What type of ejection fraction causes reduced systolic function?

A

Preserved ejection fraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are causes of heart failure?

A

Secondary to cardiac damage eg ischaemia/myopathy, hypertension, valve disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What type of ejection fraction does hypertension affect?

A

Preserved- hypertension causes thickening of the cardiac muscle wall making it harder for the muscle to relax

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What happens to cardiac output during heart failure?

A

It falls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are general symptoms of heart failure?

A

Breathlessness, fatigue, fluid retention (caused by cardiac dysfunction)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How is heart failure visible on an ECG?

A

Enlarged QRS complex (generally taller, can also be wider)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How is heart failure diagnosed?

A

Echocardiography or elevated natriuretic peptides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is Tako Tsubo syndrome?

A

Left ventricular dysfunction where apex balloons and symptoms mimic MI (myocardial infarction)- also known as broken heart syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the main cause of Tako Tsubo syndrome?

A

Stressful event

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Who does Tako Tsubo syndrome usually affect?

A

Women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

How does Tako Tsubo syndrome affect cardiac output?

A

Reduces it to around 40%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

How is Tako Tsubo syndrome visible on an ECG?

A

ST segment elevation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What are some symptoms of Tako Tsubo syndrome?

A

Chest pain, increased cardiac biomarkers but blood vessels are normal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What are conduction abnormalities?

A

Disorders that affect bioelectrical transmission along the heart

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is dilated cardiomyopathy?

A

Cardiomegaly and dilation, systolic dysfunction with

hypo-contraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What are the causes of dilated cardiomyopathy?

A

20-50% familial, also secondary to MI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

How does dilated cardiomyopathy affect cardiac output?

A

Reduces it to round 40%

24
Q

What are some symptoms of dilated cardiomyopathy?

A

Dyspnoea and fatigue

25
How is dilated cardiomyopathy visible on an ECG?
No specific changes, similar to LVR (enlarged QRS complex)
26
What is hypertrophic cardiomyopathy?
Unexplained left ventricular hypertrophy
27
What area of the heart does hypertrophic cardiomyopathy mainly affect?
Primarily affects the interventricular septum
28
What does hypertrophic cardiomyopathy do to cardiac output and how does it affect life expectancy?
Reduces cardiac output, can cause sudden death due to cardiac arrest during exercise
29
What are some symptoms of hypertrophic cardiomyopathy?
Dyspnoea and fatigue
30
How is hypertrophic cardiomyopathy visible on an ECG?
No specific changes, similar to LVR
31
What is atrial fibrillation?
Disorganised electrical activity and contraction
32
What is the cause of atrial fibrillation?
Spontaneously active cells throughout the atria
33
What effect does atrial fibrillation have on cardiac output and life expectancy?
Reduces output, leads to increased risk of heart failure or stroke
34
What are some symptoms of atrial fibrillation?
Palpitations and chest pain
35
How is atrial fibrillation visible on an ECG?
Absence of P wave and fibrillatory waves
36
What is Wolff Parkinson White?
A syndrome causing tachycardia and abnormal electrical conduction
37
What is the cause of Wolff Parkinson White?
Due to an accessory conduction pathway (bundle of Kent) between atria and ventricles
38
What effect does Wolff Parkinson White have on cardiac output and life expectancy?
Cardiac output and life expectancy remain unchanged
39
What are some symptoms of Wolff Parkinson White?
Palpitations and chest pains
40
How is Wolff Parkinson White visible on an ECG?
Pre-excitation visible on the QRS complex | Bisphasic or inverted T wave
41
What is conduction block?
Impaired electrical conduction through the AV node
42
What are the types of conduction block and how are they different?
Type 1, 2 or 3 Type 1= conduction slows down Type 2= partial block Type 3= complete block
43
What are causes of conduction block?
Fibrosis or calcification of conduction system
44
What part of the heart does type 1 conduction block affect?
AV node
45
What part of the heart do type 2 and 3 conduction block affect?
His Purkinje system
46
How are the different types of conduction block visible on an ECG?
Type I: ↑ P-R interval Type II: ↑ P-R interval and 1 beat loss of AV conduction Type III: Complete/persistent loss of conduction from atria to ventricles
47
What is a bundle branch block?
Impaired electrical conduction in the right or left | branches or fascicles of the bundles of His
48
Which out of right or left bundle branch block is more dangerous?
Left, right is benign and asymptomatic
49
How is bundle branch block visible on an ECG?
RBBB and LBBB – Widening QRS complex > 120 msec Fascicle blockage (hemi-block) – Alterations in cardiac axis: posterior leads to LAD & anterior leads to RAD
50
What clinical measurement of blood pressure qualifies as hypertension?
140/90 mmHg
51
What daytime average measurement of BP qualifies as hypertension?
135/85 mmHg
52
What does hypertension increase the risk of?
Stroke, heart disease, end organ damage
53
What are the symptoms of hypertension?
Its asymptomatic
54
Define myocardial infarction
An acute coronary syndrome resulting in cardiac tissue damage due to coronary artery blockage
55
Define angina
Pain or discomfort typically radiating from the chest
56
What are the 2 types of angina and how do they differ?
Stable- when chest pain is severe only after exertion or emotional stress Unstable- when chest pain is uncontrolled and arises even when at rest
57
What is visible on an ECG of someone with MI?
ST segment elevation