Week 7- The Cardiac Cycle Flashcards

1
Q

What are the 2 main phases of the cardiac cycle?

A

Diastole- ventricular relaxation (has 4 phases)

Systole- ventricular contraction (has 3 phases)

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2
Q

What is the stroke volume?

A

End diastolic volume - end systolic volume

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3
Q

What is the equation for ejection fraction?

A

Stroke volume divided by end diastolic volume

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4
Q

What happens to ejection fraction in those with breathlessness?

A

It is lower (around 30%)

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5
Q

What wave on an ECG signifies the start of atrial systole?

A

P wave

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6
Q

What could an abnormal 4th heart sound indicate?

A

Congestive heart failure, pulmonary embolism or tricuspid incompetence

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7
Q

What marks the start of ventricular depolarisation?

A

QRS complex

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8
Q

What is the isovolumetric contraction?

A

The interval between AV valves closing and semi lunar valves opening- contraction of ventricles with no change in volume

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9
Q

What causes the first heart sound?

A

The closure of the AV valves

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10
Q

What which phase of the cardiac cycle is there no heart sound?

A

Rapid ejection

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11
Q

State the phases of the cardiac cycle

A
Atrial systole
Isovolumetric contraction
Rapid ejection
Reduced ejection
Isovolumetric relaxation
Rapid passive filling
Reduced passive filling
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12
Q

What marks the start of rapid ejection?

A

Opening of aortic and pulmonary valves

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13
Q

What phase does reduced ejection mark the end of?

A

Systole

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14
Q

What happens during reduced ejection?

A

Aortic and pulmonary valves begin to close, blood flow from ventricles decreases and ventricular volume slowly decreases causing semilunar valves to close

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15
Q

What happens during isovolumetric relaxation?

A

AV valves remain shut until atrial pressure exceeds ventricular pressure

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16
Q

What causes the dichrotic notch?

A

Rebound pressure against aortic valve as distended aortic valve relaxes

17
Q

What causes the 2nd heart sound?

A

Closure of the semilunar valves in isovolumetric relxation

18
Q

When does rapid passive filling happen?

A

During the isoelectric flat between cardiac cycles

19
Q

What is rapid passive filling?

A

When AV valves open blood in atria flows rapidly into ventricles

20
Q

What may a 3rd heart sound indicate?

A

Turbulent ventricular filling due to hypertension or mitral incompetence

21
Q

What is reduced passive filling known as?

22
Q

What is atrial systole?

A

When the atria is almost full from passive filling due to pressure gradient, it contracts to top up blood volume in the ventricle

23
Q

What is peak systole in the pulmonary artery?

24
Q

What is the difference in volume pumped out by the right side of the heart vs the left?

A

There is no difference in volume only in pressure generated

25
What is the pressure in the systemic circuit?
120/80 mmHg
26
Where is the preload encountered on the pressure volume loop?
During diastole when blood fills the ventricle and stretches the resting ventricular muscle
27
In the pressure volume loop what represents the afterload?
Blood pressure in the aorta and pulmonary artery
28
What does increased afterload do to stroke volume and why?
Decreases stroke volume because as afterload increases the amount of shortening that occours decreases
29
Define cardiac output
Contractile capability of the heart
30
What is the equation for cardiac output?
Heart rate x stroke volume
31
How is cardiac output measured?
Ejection fraction
32
How is cardiac output increased?
Sympathetic stimulation which can be hormonal (circulating adrenaline) or neural (noradrenaline from nerves)
33
What is cardiac output at rest?
4/5 L a minute
34
What is normal heart rate at rest?
60-100 bpm