Week 8: Disorders of Ca2+ Homeostasis Flashcards by Jay Sandoval

Q

Principles of Ca2+ physiology

A

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Q

What is extracellular Ca2+ needed for?

A

is required to maintain normal biological function of nervous system and blood coagulation

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Q

What is intracellular Ca2+ needed for?

A

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Q

How does Ca2+ circulate

A

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Q

Describe the mechanisms of normal Ca2+ flux

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Q

Describe hormone and Ca2+ homeostasis

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Q

Describe Calcitonin

A

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Q

Describe PTH

A

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Q

Parathyroid glands

A

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Q

Normal parathyroid function requires how many glands

A

at least 2 of the 4 functioning glands

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Q

Renal parathyroid hormone effects

A

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Q

Bone parathyroid hormone effects

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Q

Gut parathyroid hormone effects

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Q

Interpreting PTH & Ca2+ lab tests

A

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Q

Describe Vitamin D

A

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Q

Describe Vitamin D metabolism

A

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Q

Describe Vitamin D metabolism

A

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Q

Hypocalcemia

A

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Q

DDx of hypocalcemia

A

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Q

Primary hypoparathyroidism

A

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Q

Pseudohypoparathyroidism

A

Q

Vitamin D deficiency

A

Q

Vitamin D dependent Rickets Type 1

A

Q

Vitamin D dependent Rickets Type 2

A

Q

Acute Tx of hypocalcemia

A

Q

Tx of chronic hypocalcemia

A

Q

DDx of hypercalcemia

A

Q

Complications of hypercalcemia

A

Q

Primary hyperparathyroidism

A

Q

Clinical features of HPT

A

Q

Primary Hyper PTH clinical features

A

Q

Hyper PTH Work-up

A

Q

Lab abnormalities in HPT

A

Q

Indications for surgery in primary HPT

A

Q

Other considerations for surgery for HPT

A

Q

Pre-operative imaging

A

Q

Parathyroid adenomas imaging

A

Technitium99-Sestamibi

Q

Natural Hx of Asymptomatic HPT

A

Q

Medical management primary HPT

A

Q

Familial Syndromes of HPT

A

Q

MEN syndromes

A

Q

Granulomatous Disease

A

Q

Hypercalcemia of malignancy

A

Q

Medications for hypercalcemia of malignancy

A

Q

Familial benign hypercalcemia

A

Q

Creatinine Clearance ratio

A

Q

Secondary PTH: Renal failure

A

Q

Secondary hyper-PTH

A

Q

Tertiary HPT

A

Q

Other causes of hypercalcemia

A

Q

Sally brooks

A

Q

Disorders of Ca2+ homeostasis Conclusions

A