Week 3: Small intestine motility Flashcards
Main functions of the small intestine
What are the different types of contraction patterns in the small intestine?
- Segmentation
- Peristalsis
- Migrating motor complexes
Describe segmentation contraction pattern
- Major contractile activity of the small intestine
- mixing function
Describe the peristalsis contraction pattern of the small intestine
generally short-range propulsion, 15-20/hr
Describe the Migrating Motor Complexes contraction pattern of the small intestine
Clearance at regular intervals during fasting state
What is the most common type of contraction pattern in the small intestine?
Segmentation
Function of the segmentation contraction pattern in the small intestine
effectively mixes chyme with digestive secretions “chopping” chyme as much as 8-12 times/minute
Brings fresh chyme into contact with the mucosal surface
Describe the physiology of the segmentation contraction pattern
What is the function of the peristalsis contraction pattern of the small intestine
contributes to propagation along the small intestine
Describe the physiology of the peristalsis contraction pattern of the small intestine
Describe the Migrating motor complex
How are the small intestine contractile patterns regulated?
Describe pacemaker activity in the small intestine
- electrical slow waves driven by interstitial cells of Cajal -5 sec intervals
- neuronal and hormonal activity act on top of slow waves to determine contractility
Electrical slow waves
Electrical slow waves
Electrical slow waves
Electrical slow waves
Describe the hormonal regulation of motility
Describe releasers of Gastrointestinal hormones