Week 4: Regulation of glycolysis Flashcards
1
Q
hexokinase inhibited by
A
glucose-6-phosphate
2
Q
When is it important to regulate hexokinase
A
RBCs because GLUT-1 is constitutive high-affinity glucose transporter
3
Q
PFK-1 regulation
A
inhibited by ATP
activated by AMP
4
Q
ADP metabolism
A
2 ADP -adenalyl kinase-> ATP + AMP
5
Q
pyruvate kinase regulation
A
fructose-1, 6-bisphosphate feed-forward regulation because from Fructose-1, 6-bisphosphate to phosphoenolpyruvate are reversible and body doesn’t want the reverse reactions when it needs energy