Week 6 - GI Ulcers Flashcards

1
Q

What is the action and effects of Peptic Ulcers?

A
  • Erosion of gastricor duodenal lining
  • Exposure of submucosa to low pH
  • Capillary erosion = bleeding
  • Nerve exposure = pain
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2
Q

What are the 3 main causes of Ulcers?

A
  • Helicobacter pylori infection
  • Excessive anti-inflammatory use (eg., aspirin)
  • Excessive gastric secretion
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3
Q

What is the treatment of Ulcers?

A
  • Suppress gastric acid production
  • Avoid NSAIDs
  • Eradicate Helibacter
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4
Q

How is Helicobacter Pylori eradicated?

A
  • Antibiotics - Amoxicillin
  • H2 blockers - ranitidine
  • PPI - omeprazole
  • stomach-lining protector - bismuth subsalicylate
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