Week 10 - Drugs Dependance

Question 1

What are the two main arms of dependance?

Answer 1

• Physical - (withdrawal)

- Psychological - (cravings)

Question 2

Which of Physical and Psychological dependance is the major factor leading to relapse?

Answer 2

Psychological

Question 3

What are the approaches to treating drug dependace?

Answer 3

• Substitution to alleviate withdrawal symptoms
• Long-term substitution
• Blocking response
• Aversive therapies
• Modification of craving

Question 4

What are examples of Substitution?

Answer 4

Methadone
-used short term to blunt opiate withdrawal
Benzodiazapines
-blunt alcohol withdrawal

Question 5

What are examples of Long-term substitution?

Answer 5

Methadone
-substitute opiate addiction
Nicotine patches or gum

Question 6

What are examples of Blocking response?

Answer 6

Naltrexone
-block opiate effects
Mecamylamine
-block nicotine effects

Question 7

What are examples of Aversive therapies?

Answer 7

Disulfiram

-induce unpleasant response to ethanol

Question 8

What are examples of Modification of craving?

Answer 8

Bupropion - antidepressant
Naltrexone - block opiates
Clonidine - a-adrenorecepto agonist
Acamprosate - NMDA-receptor antagonist